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Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review

Malignant rhabdoid tumors (MRTs) are rare tumors with high mortality rates and poor prognoses. MRTs occur mainly in the central nervous system, kidneys, and soft tissues, but rarely in the omentum. MRTs occur more commonly in infants and children and less frequently in adults. Here, we report the fi...

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Autores principales: Zhou, Xunjian, Duan, Zhi, Tao, Ting, Li, Zhen, Wang, Ning, Xu, Qimei, Wei, Meiyan, Zhong, Zheng, Liu, Ran, Yin, Qinghua, Xiong, Lixin, Chen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473875/
https://www.ncbi.nlm.nih.gov/pubmed/37664039
http://dx.doi.org/10.3389/fonc.2023.1230021
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author Zhou, Xunjian
Duan, Zhi
Tao, Ting
Li, Zhen
Wang, Ning
Xu, Qimei
Wei, Meiyan
Zhong, Zheng
Liu, Ran
Yin, Qinghua
Xiong, Lixin
Chen, Hui
author_facet Zhou, Xunjian
Duan, Zhi
Tao, Ting
Li, Zhen
Wang, Ning
Xu, Qimei
Wei, Meiyan
Zhong, Zheng
Liu, Ran
Yin, Qinghua
Xiong, Lixin
Chen, Hui
author_sort Zhou, Xunjian
collection PubMed
description Malignant rhabdoid tumors (MRTs) are rare tumors with high mortality rates and poor prognoses. MRTs occur mainly in the central nervous system, kidneys, and soft tissues, but rarely in the omentum. MRTs occur more commonly in infants and children and less frequently in adults. Here, we report the first observed case of MRT in an adult omentum. A 35-year-old man with abdominal distension and pain was admitted to the emergency department. Previously, several hospitals considered patients with cirrhosis who had not received active treatment. Computed tomography and magnetic resonance imaging revealed diffuse omental thickening and massive ascites. The surgery was performed at our hospital, and the pathological diagnosis was MRT with a SMARCB1(INI-1) deletion. Postoperatively, his symptoms improved, and he underwent five cycles of chemotherapy. However, 6 months after surgery, the tumor developed liver metastases, and the patient subsequently died. Primary MRT of the greater omentum is rare, and its pathological diagnosis usually requires extensive clinicopathological evaluation of various differential diagnoses and an appropriate work-up to exclude other malignancies associated with SMARCB1 deletion. At the same time, the lack of specific signs of omental MRT and its rapid progression should alert clinicians.
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spelling pubmed-104738752023-09-02 Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review Zhou, Xunjian Duan, Zhi Tao, Ting Li, Zhen Wang, Ning Xu, Qimei Wei, Meiyan Zhong, Zheng Liu, Ran Yin, Qinghua Xiong, Lixin Chen, Hui Front Oncol Oncology Malignant rhabdoid tumors (MRTs) are rare tumors with high mortality rates and poor prognoses. MRTs occur mainly in the central nervous system, kidneys, and soft tissues, but rarely in the omentum. MRTs occur more commonly in infants and children and less frequently in adults. Here, we report the first observed case of MRT in an adult omentum. A 35-year-old man with abdominal distension and pain was admitted to the emergency department. Previously, several hospitals considered patients with cirrhosis who had not received active treatment. Computed tomography and magnetic resonance imaging revealed diffuse omental thickening and massive ascites. The surgery was performed at our hospital, and the pathological diagnosis was MRT with a SMARCB1(INI-1) deletion. Postoperatively, his symptoms improved, and he underwent five cycles of chemotherapy. However, 6 months after surgery, the tumor developed liver metastases, and the patient subsequently died. Primary MRT of the greater omentum is rare, and its pathological diagnosis usually requires extensive clinicopathological evaluation of various differential diagnoses and an appropriate work-up to exclude other malignancies associated with SMARCB1 deletion. At the same time, the lack of specific signs of omental MRT and its rapid progression should alert clinicians. Frontiers Media S.A. 2023-08-18 /pmc/articles/PMC10473875/ /pubmed/37664039 http://dx.doi.org/10.3389/fonc.2023.1230021 Text en Copyright © 2023 Zhou, Duan, Tao, Li, Wang, Xu, Wei, Zhong, Liu, Yin, Xiong and Chen https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Zhou, Xunjian
Duan, Zhi
Tao, Ting
Li, Zhen
Wang, Ning
Xu, Qimei
Wei, Meiyan
Zhong, Zheng
Liu, Ran
Yin, Qinghua
Xiong, Lixin
Chen, Hui
Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review
title Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review
title_full Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review
title_fullStr Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review
title_full_unstemmed Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review
title_short Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review
title_sort malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473875/
https://www.ncbi.nlm.nih.gov/pubmed/37664039
http://dx.doi.org/10.3389/fonc.2023.1230021
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