Acute pancreatitis following endoscopic ampullary biopsy: A case report

BACKGROUND: Endoscopic biopsy is mandatory for the diagnosis of malignant and premalignant ampullary tumours. The commonly reported inadvertent complications following routine mucosal biopsy include perforation and haemorrhage. Acute pancreatitis is an extremely rare complication following this procedure. CASE SUMMARY: This report details the case of a 59-year-old man who underwent biopsy of the ampulla for a suspected periampullary tumour. Following the procedure, the patient presented with symptoms of acute pancreatitis which was substantiated by laboratory and radiological investigations. He was conservatively managed and discharged following complete resolution of symptoms. CONCLUSION: This case report serves to highlight the importance of this potential complication following routine endoscopic biopsy of the ampulla.