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Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up

Sclerosing/spindle cell rhabdomyosarcoma (s-scRMS) is a rare variant of striated muscle tumours. It has been recognised as an individual entity, the fourth subtype of rhabdomyosarcoma in the latest WHO classification. In the paediatric population, it occurs more commonly in the paratesticular area,...

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Autores principales: Othman, Homihidayah, Mohamed Haflah, Nor Hazla, Sani, Mohamed H, Wan Ismail, Wan Faisham, Kesu Belani, Levin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473976/
https://www.ncbi.nlm.nih.gov/pubmed/37664329
http://dx.doi.org/10.7759/cureus.42869
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author Othman, Homihidayah
Mohamed Haflah, Nor Hazla
Sani, Mohamed H
Wan Ismail, Wan Faisham
Kesu Belani, Levin
author_facet Othman, Homihidayah
Mohamed Haflah, Nor Hazla
Sani, Mohamed H
Wan Ismail, Wan Faisham
Kesu Belani, Levin
author_sort Othman, Homihidayah
collection PubMed
description Sclerosing/spindle cell rhabdomyosarcoma (s-scRMS) is a rare variant of striated muscle tumours. It has been recognised as an individual entity, the fourth subtype of rhabdomyosarcoma in the latest WHO classification. In the paediatric population, it occurs more commonly in the paratesticular area, whereas in adults, it occurs more commonly in the head and neck region. It has distinctive characteristics in terms of its histopathological and immunochemistry findings, which help in accurate diagnosis. The mainstay of treatment is a multimodal approach, i.e., surgery, chemotherapy, and radiation therapy. However, no standard care is still being established internationally for adult cases. In adults, this tumour has a poorer prognosis as compared to children. We describe a patient with s-scRMS of the lower limb who has undergone wide local resection of the tumour with surgical reconstruction of the distal tibiofibular joint with autograft and its two-year outcome.
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spelling pubmed-104739762023-09-03 Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up Othman, Homihidayah Mohamed Haflah, Nor Hazla Sani, Mohamed H Wan Ismail, Wan Faisham Kesu Belani, Levin Cureus Oncology Sclerosing/spindle cell rhabdomyosarcoma (s-scRMS) is a rare variant of striated muscle tumours. It has been recognised as an individual entity, the fourth subtype of rhabdomyosarcoma in the latest WHO classification. In the paediatric population, it occurs more commonly in the paratesticular area, whereas in adults, it occurs more commonly in the head and neck region. It has distinctive characteristics in terms of its histopathological and immunochemistry findings, which help in accurate diagnosis. The mainstay of treatment is a multimodal approach, i.e., surgery, chemotherapy, and radiation therapy. However, no standard care is still being established internationally for adult cases. In adults, this tumour has a poorer prognosis as compared to children. We describe a patient with s-scRMS of the lower limb who has undergone wide local resection of the tumour with surgical reconstruction of the distal tibiofibular joint with autograft and its two-year outcome. Cureus 2023-08-02 /pmc/articles/PMC10473976/ /pubmed/37664329 http://dx.doi.org/10.7759/cureus.42869 Text en Copyright © 2023, Othman et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Othman, Homihidayah
Mohamed Haflah, Nor Hazla
Sani, Mohamed H
Wan Ismail, Wan Faisham
Kesu Belani, Levin
Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up
title Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up
title_full Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up
title_fullStr Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up
title_full_unstemmed Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up
title_short Distal Tibiofibular Joint Reconstruction Using Autograft in a Rare Case of Lower Limb Sclerosing/Spindle Cell Rhabdomyosarcoma: A Two-Year Follow-Up
title_sort distal tibiofibular joint reconstruction using autograft in a rare case of lower limb sclerosing/spindle cell rhabdomyosarcoma: a two-year follow-up
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473976/
https://www.ncbi.nlm.nih.gov/pubmed/37664329
http://dx.doi.org/10.7759/cureus.42869
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