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A molecular analysis of substituted phenylethylamines as potential microtubule targeting agents through in silico methods and in vitro microtubule-polymerization activity
Natural phenethylamines are trace amine neurotransmitters associated with dopamine transmission and related illnesses such Parkinson’s disease, and addiction. Synthetic phenethylamines can have psychoactive and hallucinogenic effects due to their high affinity with the 5-HT(2A) receptor. Evidence in...
Autores principales: | De Abreu, Isadora Rocha, Barkdull, Allison, Munoz, James R., Smith, Robert P., Craddock, Travis J. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474033/ https://www.ncbi.nlm.nih.gov/pubmed/37658096 http://dx.doi.org/10.1038/s41598-023-41600-9 |
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