Cargando…

Reg3γ: current understanding and future therapeutic opportunities in metabolic disease

Regenerating family member gamma, Reg3γ (the mouse homolog of human REG3A), belonging to the antimicrobial peptides (AMPs), functions as a part of the host immune system to maintain spatial segregation between the gut bacteria and the host in the intestine via bactericidal activity. There is emergin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Jae Hoon, Bozadjieva-Kramer, Nadejda, Seeley, Randy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474034/ https://www.ncbi.nlm.nih.gov/pubmed/37524871 http://dx.doi.org/10.1038/s12276-023-01054-5

Ejemplares similares

Targeting FXR and FGF19 to Treat Metabolic Diseases—Lessons Learned From Bariatric Surgery
por: Bozadjieva, Nadejda, et al.
Publicado: (2018)

Vertical sleeve gastrectomy increases duodenal Lactobacillus spp. richness associated with the activation of intestinal HIF2α signaling and metabolic benefits
por: Shao, Yikai, et al.
Publicado: (2022)

The Role of Elevated Branched-Chain Amino Acids in the Effects of Vertical Sleeve Gastrectomy to Reduce Weight and Improve Glucose Regulation
por: Kramer, Nadejda Bozadjieva, et al.
Publicado: (2020)

Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion
por: Evers, Simon S., et al.
Publicado: (2022)

Regulation of Life & Death by REGγ
por: Funderburk, Keaton E., et al.
Publicado: (2022)

Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice
por: Bozadjieva-Kramer, Nadejda, et al.
Publicado: (2021)

Myocardial Accumulations of Reg3A, Reg3γ and Oncostatin M Are Associated with the Formation of Granulomata in Patients with Cardiac Sarcoidosis
por: Gajawada, Praveen, et al.
Publicado: (2021)

OR24-4 Targeting Hyperglucagonemia Reverses Glucagon Resistance
por: Bernal-Mizrachi, Ernesto, et al.
Publicado: (2022)

Risks and Opportunities of RegTech and SupTech Developments
por: Gasparri, Giorgio
Publicado: (2019)

Epilepsy in Dravet Syndrome—Current and Future Therapeutic Opportunities
por: Gao, Chao, et al.
Publicado: (2023)

REGγ is associated with multiple oncogenic pathways in human cancers
por: He, Jing, et al.
Publicado: (2012)

Regulation of energy homeostasis by the ubiquitin-independent REGγ proteasome
por: Sun, Lianhui, et al.
Publicado: (2016)

REGγ Contributes to Regulation of Hemoglobin and Hemoglobin δ Subunit
por: Zuo, Qiuhong, et al.
Publicado: (2017)

Aging-associated REGγ proteasome decline predisposes to tauopathy
por: Tu, Jialu, et al.
Publicado: (2022)

Mucin Muc2 Deficiency and Weaning Influences the Expression of the Innate Defense Genes Reg3β, Reg3γ and Angiogenin-4
por: Burger-van Paassen, Nanda, et al.
Publicado: (2012)

Endothelial senescence in vascular diseases: current understanding and future opportunities in senotherapeutics
por: Han, Yeaeun, et al.
Publicado: (2023)

Entrepreneurial experimentation in business model dynamics: Current understanding and future opportunities
por: Sanasi, Silvia
Publicado: (2023)

Four Decades After the Discovery of Regenerating Islet-Derived (Reg) Proteins: Current Understanding and Challenges
por: Chen, Zijing, et al.
Publicado: (2019)

REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase
por: Uchimura, Yasuhiro, et al.
Publicado: (2011)

GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion
por: Zhang, Hui, et al.
Publicado: (2023)

Therapeutic resistance in pancreatic ductal adenocarcinoma: Current challenges and future opportunities
por: Jain, Aditi, et al.
Publicado: (2021)

REGγ Is Associated with Lymph Node Metastasis and T-Stage in Papillary Thyroid Carcinoma
por: Qi, Long, et al.
Publicado: (2018)

The REGγ-Proteasome Regulates Spermatogenesis Partially by P53-PLZF Signaling
por: Gao, Xiao, et al.
Publicado: (2019)

REGγ regulates circadian clock by modulating BMAL1 protein stability
por: Kubra, Syeda, et al.
Publicado: (2021)

Time-dependent effects of endogenous hyperglucagonemia on glucose homeostasis and hepatic glucagon action
por: Lubaczeuski, Camila, et al.
Publicado: (2023)

Ruminococcus gnavus and Limosilactobacillus reuteri Regulate Reg3γ Expression through Multiple Pathways
por: Ramirez, Zeni E., et al.
Publicado: (2023)

Understanding Drivers of Ocular Fibrosis: Current and Future Therapeutic Perspectives
por: Mallone, Fabiana, et al.
Publicado: (2021)

Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance
por: Rupp, Alan C., et al.
Publicado: (2018)

Current Understanding on the Metabolism of Neutrophils
por: Jeon, Jae-Han, et al.
Publicado: (2020)

Understanding Metabolic Regulation Between Host and Pathogens: New Opportunities for the Development of Improved Therapeutic Strategies Against Mycobacterium tuberculosis Infection
por: Park, Ji-Hae, et al.
Publicado: (2021)

PPARγ is a major driver of the accumulation and phenotype of adipose-tissue T(reg) cells
por: Cipolletta, Daniela, et al.
Publicado: (2012)

REG γ knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma
por: Yin, Zhiqiang, et al.
Publicado: (2020)

Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities
por: Xiong, Ye, et al.
Publicado: (2018)

Photoreceptor metabolic reprogramming: current understanding and therapeutic implications
por: Pan, Warren W., et al.
Publicado: (2021)

Interleukin-33 Promotes REG3γ Expression in Intestinal Epithelial Cells and Regulates Gut Microbiota
por: Xiao, Yi, et al.
Publicado: (2019)

Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia
por: Bozadjieva Kramer, Nadejda, et al.
Publicado: (2021)

Female Oncofertility: Current Understandings, Therapeutic Approaches, Controversies, and Future Perspectives
por: Vo, Kim Cat Tuyen, et al.
Publicado: (2021)

Genetics of Generalized Pustular Psoriasis: Current Understanding and Implications for Future Therapeutics
por: Yang, Syuan-Fei, et al.
Publicado: (2023)

Continuous glucose monitoring reveals glycemic variability and hypoglycemia after vertical sleeve gastrectomy in rats
por: Evers, Simon S., et al.
Publicado: (2019)

Future challenges and therapeutic opportunities in type 2 diabetes: Changing the paradigm of current therapy
por: Owens, David R., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2v61j5hlfa79vtbks19ev2bn69