Targeting transforming growth factor beta (TGF-β) using Pirfenidone, a potential repurposing therapeutic strategy in colorectal cancer

The modulating factors within the tumor microenvironment, for example, transforming growth factor beta (TGF-β), may limit the response to chemo and immunotherapy protocols in colorectal cancer (CRC). In the current study, the therapeutic potential of targeting the TGF-β pathway using Pirfenidone (PF...

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Detalles Bibliográficos
Autores principales: Jamialahmadi, Hamid, Nazari, Seyedeh Elnaz, TanzadehPanah, Hamid, Saburi, Ehsan, Asgharzadeh, Fereshteh, Khojasteh-Leylakoohi, Fatemeh, Alaei, Maryam, Mirahmadi, Mahdi, Babaei, Fatemeh, Asghari, Seyedeh Zahra, Mansouri, Saeide, Khalili-Tanha, Ghazaleh, Maftooh, Mina, Fiuji, Hamid, Hassanian, Seyed Mahdi, Ferns, Gordon A., Khazaei, Majid, Avan, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474052/
https://www.ncbi.nlm.nih.gov/pubmed/37658230
http://dx.doi.org/10.1038/s41598-023-41550-2

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