Tumor-associated macrophages confer colorectal cancer 5-fluorouracil resistance by promoting MRP1 membrane translocation via an intercellular CXCL17/CXCL22–CCR4–ATF6–GRP78 axis

Chemotherapy represents a major type of clinical treatment against colorectal cancer (CRC). Aberrant drug efflux mediated by transporters acts as a key approach for tumor cells to acquire chemotherapy resistance. Increasing evidence implies that tumor-associated macrophages (TAMs) play a pivotal rol...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lichao, Lu, Xiaoqing, Xu, Yuanzhi, La, Xiaoqin, Tian, Jinmiao, Li, Aiping, Li, Hanqing, Wu, Changxin, Xi, Yanfeng, Song, Guisheng, Zhou, Zhaocai, Bai, Wenqi, An, Liwei, Li, Zhuoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474093/
https://www.ncbi.nlm.nih.gov/pubmed/37658050
http://dx.doi.org/10.1038/s41419-023-06108-0

Ejemplares similares

Ejemplares similares