Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis

Oxaliplatin is widely used in chemotherapy for colorectal cancer (CRC), but its sensitivity has become a major obstacle to limiting efficacy. Many literatures reported that Nrf2 activation promoted tumor chemoresistance. In this study, we explored the role and mechanism of Nrf2 inhibition in oxalipl...

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Detalles Bibliográficos
Autores principales: Huang, Yongzhou, Yang, Wenchang, Yang, Lei, Wang, Tao, Li, Chengguo, Yu, Jiaxian, Zhang, Peng, Yin, Yuping, Li, Ruidong, Tao, Kaixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474100/
https://www.ncbi.nlm.nih.gov/pubmed/37658132
http://dx.doi.org/10.1038/s41598-023-41490-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474100/
https://www.ncbi.nlm.nih.gov/pubmed/37658132
http://dx.doi.org/10.1038/s41598-023-41490-x

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