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Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate. Further, studies are required to investigate the key factors of vector-borne infections to provide effective contr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474157/ https://www.ncbi.nlm.nih.gov/pubmed/37658134 http://dx.doi.org/10.1038/s41598-023-41440-7 |
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author | Tang, Tao-Qian Jan, Rashid Khurshaid, Adil Shah, Zahir Vrinceanu, Narcisa Racheriu, Mihaela |
author_facet | Tang, Tao-Qian Jan, Rashid Khurshaid, Adil Shah, Zahir Vrinceanu, Narcisa Racheriu, Mihaela |
author_sort | Tang, Tao-Qian |
collection | PubMed |
description | The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate. Further, studies are required to investigate the key factors of vector-borne infections to provide effective control measure. This study focuses on formulating a mathematical framework to characterize the spread of chikungunya infection in the presence of vaccines and treatments. The research is primarily dedicated to descriptive study and comprehension of dynamic behaviour of chikungunya dynamics. We use Banach’s and Schaefer’s fixed point theorems to investigate the existence and uniqueness of the suggested chikungunya framework resolution. Additionally, we confirm the Ulam–Hyers stability of the chikungunya system. To assess the impact of various parameters on the dynamics of chikungunya, we examine solution pathways using the Laplace-Adomian method of disintegration. Specifically, to visualise the impacts of fractional order, vaccination, bite rate and treatment computer algorithms are employed on the infection level of chikungunya. Our research identified the framework’s essential input settings for managing chikungunya infection. Notably, the intensity of chikungunya infection can be reduced by lowering mosquito bite rates in the affected area. On the other hand, vaccination, memory index or fractional order, and treatment could be used as efficient controlling variables. |
format | Online Article Text |
id | pubmed-10474157 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-104741572023-09-03 Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective Tang, Tao-Qian Jan, Rashid Khurshaid, Adil Shah, Zahir Vrinceanu, Narcisa Racheriu, Mihaela Sci Rep Article The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate. Further, studies are required to investigate the key factors of vector-borne infections to provide effective control measure. This study focuses on formulating a mathematical framework to characterize the spread of chikungunya infection in the presence of vaccines and treatments. The research is primarily dedicated to descriptive study and comprehension of dynamic behaviour of chikungunya dynamics. We use Banach’s and Schaefer’s fixed point theorems to investigate the existence and uniqueness of the suggested chikungunya framework resolution. Additionally, we confirm the Ulam–Hyers stability of the chikungunya system. To assess the impact of various parameters on the dynamics of chikungunya, we examine solution pathways using the Laplace-Adomian method of disintegration. Specifically, to visualise the impacts of fractional order, vaccination, bite rate and treatment computer algorithms are employed on the infection level of chikungunya. Our research identified the framework’s essential input settings for managing chikungunya infection. Notably, the intensity of chikungunya infection can be reduced by lowering mosquito bite rates in the affected area. On the other hand, vaccination, memory index or fractional order, and treatment could be used as efficient controlling variables. Nature Publishing Group UK 2023-09-01 /pmc/articles/PMC10474157/ /pubmed/37658134 http://dx.doi.org/10.1038/s41598-023-41440-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Tang, Tao-Qian Jan, Rashid Khurshaid, Adil Shah, Zahir Vrinceanu, Narcisa Racheriu, Mihaela Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective |
title | Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective |
title_full | Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective |
title_fullStr | Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective |
title_full_unstemmed | Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective |
title_short | Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective |
title_sort | analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474157/ https://www.ncbi.nlm.nih.gov/pubmed/37658134 http://dx.doi.org/10.1038/s41598-023-41440-7 |
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