Cargando…

Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective

The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate. Further, studies are required to investigate the key factors of vector-borne infections to provide effective contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Tao-Qian, Jan, Rashid, Khurshaid, Adil, Shah, Zahir, Vrinceanu, Narcisa, Racheriu, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474157/
https://www.ncbi.nlm.nih.gov/pubmed/37658134
http://dx.doi.org/10.1038/s41598-023-41440-7
_version_ 1785100430528741376
author Tang, Tao-Qian
Jan, Rashid
Khurshaid, Adil
Shah, Zahir
Vrinceanu, Narcisa
Racheriu, Mihaela
author_facet Tang, Tao-Qian
Jan, Rashid
Khurshaid, Adil
Shah, Zahir
Vrinceanu, Narcisa
Racheriu, Mihaela
author_sort Tang, Tao-Qian
collection PubMed
description The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate. Further, studies are required to investigate the key factors of vector-borne infections to provide effective control measure. This study focuses on formulating a mathematical framework to characterize the spread of chikungunya infection in the presence of vaccines and treatments. The research is primarily dedicated to descriptive study and comprehension of dynamic behaviour of chikungunya dynamics. We use Banach’s and Schaefer’s fixed point theorems to investigate the existence and uniqueness of the suggested chikungunya framework resolution. Additionally, we confirm the Ulam–Hyers stability of the chikungunya system. To assess the impact of various parameters on the dynamics of chikungunya, we examine solution pathways using the Laplace-Adomian method of disintegration. Specifically, to visualise the impacts of fractional order, vaccination, bite rate and treatment computer algorithms are employed on the infection level of chikungunya. Our research identified the framework’s essential input settings for managing chikungunya infection. Notably, the intensity of chikungunya infection can be reduced by lowering mosquito bite rates in the affected area. On the other hand, vaccination, memory index or fractional order, and treatment could be used as efficient controlling variables.
format Online
Article
Text
id pubmed-10474157
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-104741572023-09-03 Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective Tang, Tao-Qian Jan, Rashid Khurshaid, Adil Shah, Zahir Vrinceanu, Narcisa Racheriu, Mihaela Sci Rep Article The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate. Further, studies are required to investigate the key factors of vector-borne infections to provide effective control measure. This study focuses on formulating a mathematical framework to characterize the spread of chikungunya infection in the presence of vaccines and treatments. The research is primarily dedicated to descriptive study and comprehension of dynamic behaviour of chikungunya dynamics. We use Banach’s and Schaefer’s fixed point theorems to investigate the existence and uniqueness of the suggested chikungunya framework resolution. Additionally, we confirm the Ulam–Hyers stability of the chikungunya system. To assess the impact of various parameters on the dynamics of chikungunya, we examine solution pathways using the Laplace-Adomian method of disintegration. Specifically, to visualise the impacts of fractional order, vaccination, bite rate and treatment computer algorithms are employed on the infection level of chikungunya. Our research identified the framework’s essential input settings for managing chikungunya infection. Notably, the intensity of chikungunya infection can be reduced by lowering mosquito bite rates in the affected area. On the other hand, vaccination, memory index or fractional order, and treatment could be used as efficient controlling variables. Nature Publishing Group UK 2023-09-01 /pmc/articles/PMC10474157/ /pubmed/37658134 http://dx.doi.org/10.1038/s41598-023-41440-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Tang, Tao-Qian
Jan, Rashid
Khurshaid, Adil
Shah, Zahir
Vrinceanu, Narcisa
Racheriu, Mihaela
Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
title Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
title_full Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
title_fullStr Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
title_full_unstemmed Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
title_short Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
title_sort analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474157/
https://www.ncbi.nlm.nih.gov/pubmed/37658134
http://dx.doi.org/10.1038/s41598-023-41440-7
work_keys_str_mv AT tangtaoqian analysisofthedynamicsofavectorborneinfectionwiththeeffectofimperfectvaccinationfromafractionalperspective
AT janrashid analysisofthedynamicsofavectorborneinfectionwiththeeffectofimperfectvaccinationfromafractionalperspective
AT khurshaidadil analysisofthedynamicsofavectorborneinfectionwiththeeffectofimperfectvaccinationfromafractionalperspective
AT shahzahir analysisofthedynamicsofavectorborneinfectionwiththeeffectofimperfectvaccinationfromafractionalperspective
AT vrinceanunarcisa analysisofthedynamicsofavectorborneinfectionwiththeeffectofimperfectvaccinationfromafractionalperspective
AT racheriumihaela analysisofthedynamicsofavectorborneinfectionwiththeeffectofimperfectvaccinationfromafractionalperspective