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Challenges in the determination of total vitamin B12 by cyanidation conversion: insights from stable isotope dilution assays

Previous methods for vitamin B12 (B12) analysis have extensively used cyanidation conversion with the intention of converting all cobalamins to cyanocobalamin (CNCbl) for total B12 determination. This approach has been favored for its advantages in reducing the number of analytes, increasing analyte...

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Detalles Bibliográficos
Autores principales: Wang, Mengle, Schuster, Kathrin, Asam, Stefan, Rychlik, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474169/
https://www.ncbi.nlm.nih.gov/pubmed/37466679
http://dx.doi.org/10.1007/s00216-023-04860-y