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The NEDD8-activating enzyme E1 UBA3 orchestrates the immunosuppressive microenvironment in lung adenocarcinoma via the NF-кB pathway

Immunosuppressive cells play important roles in generating an immunosuppressive tumor microenvironment and facilitating tumor immune escape. However, the molecular mechanisms underlying their immunosuppressive effects remain unclear. UBA3, the sole catalytic subunit of the neural precursor cell expr...

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Detalles Bibliográficos
Autores principales: Lin, Xiongzhi, Yang, Shuhan, Zhou, Caichuan, Ao, Chengcheng, Sun, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474176/
https://www.ncbi.nlm.nih.gov/pubmed/37656220
http://dx.doi.org/10.1007/s12032-023-02162-y