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The NEDD8-activating enzyme E1 UBA3 orchestrates the immunosuppressive microenvironment in lung adenocarcinoma via the NF-кB pathway
Immunosuppressive cells play important roles in generating an immunosuppressive tumor microenvironment and facilitating tumor immune escape. However, the molecular mechanisms underlying their immunosuppressive effects remain unclear. UBA3, the sole catalytic subunit of the neural precursor cell expr...
Autores principales: | Lin, Xiongzhi, Yang, Shuhan, Zhou, Caichuan, Ao, Chengcheng, Sun, Dongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474176/ https://www.ncbi.nlm.nih.gov/pubmed/37656220 http://dx.doi.org/10.1007/s12032-023-02162-y |
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