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Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM)
Whilst the finding of heritable susceptibility to disease was once relatively rare, mainstreaming of genetic testing has resulted in a steady increase. Patients are often encouraged to share their genetic test results with relevant relatives, but relatives may not receive this information, leaving t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474271/ https://www.ncbi.nlm.nih.gov/pubmed/37344572 http://dx.doi.org/10.1038/s41431-023-01400-1 |
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author | Ballard, Lisa Marie Band, Rebecca Lucassen, Anneke M. |
author_facet | Ballard, Lisa Marie Band, Rebecca Lucassen, Anneke M. |
author_sort | Ballard, Lisa Marie |
collection | PubMed |
description | Whilst the finding of heritable susceptibility to disease was once relatively rare, mainstreaming of genetic testing has resulted in a steady increase. Patients are often encouraged to share their genetic test results with relevant relatives, but relatives may not receive this information, leaving them without knowledge of their own risk. Therefore, strategies to help communicate such information are important. This review aimed to explore the efficacy of existing interventions to improve the sharing of genetic test results. A synthesis without meta-analysis design was used. A systematic search of Medline, CINAHL, PsychINFO, and AMED was conducted, and five studies were identified worldwide. Data were extracted for each study regarding study aim, participant characteristics, condition, intervention details, comparison, study duration, outcome measures, theory and behaviour change techniques used. Limited efficacy and application of theory was found. Knowledge, motivation and self-efficacy were not increased in any intervention. No gender differences in communication behaviour were encountered in interventions that recruited men and women. Two studies reported an evaluation of acceptability, which showed that the interventions were well received by patients and health professionals. No study reported the involvement of the target population in any phase of intervention development. Given the lack of health psychology-informed interventions in this area of clinical genetics, we recommend genetic health professionals, health psychologists and patients collaborate on all stages of future interventions that involve the cascading of genetic health information within families. We also provide guidance regarding use of theory and intervention elements for future intervention development. |
format | Online Article Text |
id | pubmed-10474271 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-104742712023-09-03 Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM) Ballard, Lisa Marie Band, Rebecca Lucassen, Anneke M. Eur J Hum Genet Review Article Whilst the finding of heritable susceptibility to disease was once relatively rare, mainstreaming of genetic testing has resulted in a steady increase. Patients are often encouraged to share their genetic test results with relevant relatives, but relatives may not receive this information, leaving them without knowledge of their own risk. Therefore, strategies to help communicate such information are important. This review aimed to explore the efficacy of existing interventions to improve the sharing of genetic test results. A synthesis without meta-analysis design was used. A systematic search of Medline, CINAHL, PsychINFO, and AMED was conducted, and five studies were identified worldwide. Data were extracted for each study regarding study aim, participant characteristics, condition, intervention details, comparison, study duration, outcome measures, theory and behaviour change techniques used. Limited efficacy and application of theory was found. Knowledge, motivation and self-efficacy were not increased in any intervention. No gender differences in communication behaviour were encountered in interventions that recruited men and women. Two studies reported an evaluation of acceptability, which showed that the interventions were well received by patients and health professionals. No study reported the involvement of the target population in any phase of intervention development. Given the lack of health psychology-informed interventions in this area of clinical genetics, we recommend genetic health professionals, health psychologists and patients collaborate on all stages of future interventions that involve the cascading of genetic health information within families. We also provide guidance regarding use of theory and intervention elements for future intervention development. Springer International Publishing 2023-06-21 2023-09 /pmc/articles/PMC10474271/ /pubmed/37344572 http://dx.doi.org/10.1038/s41431-023-01400-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Article Ballard, Lisa Marie Band, Rebecca Lucassen, Anneke M. Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM) |
title | Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM) |
title_full | Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM) |
title_fullStr | Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM) |
title_full_unstemmed | Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM) |
title_short | Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM) |
title_sort | interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (swim) |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474271/ https://www.ncbi.nlm.nih.gov/pubmed/37344572 http://dx.doi.org/10.1038/s41431-023-01400-1 |
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