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The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic, fatal, fibrotic, interstitial lung disease of unknown cause. Despite extensive studies, the underlying mechanisms of IPF development remain unknown. Here, we found that p300 was upregulated in multiple epithelial cells in lung samples from patients w...

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Detalles Bibliográficos
Autores principales: Lee, Soo Yeon, Park, Soo-Yeon, Lee, Seung-Hyun, Kim, Hyunsik, Kwon, Jae-Hwan, Yoo, Jung-Yoon, Kim, Kyunggon, Park, Moo Suk, Lee, Chun Geun, Elias, Jack A., Sohn, Myung Hyun, Shim, Hyo Sup, Yoon, Ho-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474292/
https://www.ncbi.nlm.nih.gov/pubmed/37524875
http://dx.doi.org/10.1038/s12276-023-01066-1