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The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic, fatal, fibrotic, interstitial lung disease of unknown cause. Despite extensive studies, the underlying mechanisms of IPF development remain unknown. Here, we found that p300 was upregulated in multiple epithelial cells in lung samples from patients w...
Autores principales: | Lee, Soo Yeon, Park, Soo-Yeon, Lee, Seung-Hyun, Kim, Hyunsik, Kwon, Jae-Hwan, Yoo, Jung-Yoon, Kim, Kyunggon, Park, Moo Suk, Lee, Chun Geun, Elias, Jack A., Sohn, Myung Hyun, Shim, Hyo Sup, Yoon, Ho-Geun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474292/ https://www.ncbi.nlm.nih.gov/pubmed/37524875 http://dx.doi.org/10.1038/s12276-023-01066-1 |
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