METTL3‐stabilized super enhancers‐lncRNA SUCLG2‐AS1 mediates the formation of a long‐range chromatin loop between enhancers and promoters of SOX2 in metastasis and radiosensitivity of nasopharyngeal carcinoma

BACKGROUND: Super enhancers (SE) play pivotal roles in cell identity and diseases occur including tumorigenesis. The depletion of SE‐associated lncRNA transcripts, also known as super‐lncRNA, causes the activity of SE to be dysregulated. METHODS: We screened and identified an elevated metastasis‐ass...

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Detalles Bibliográficos
Autores principales: Hu, Xinyu, Wu, Jianfeng, Feng, Yong, Ma, Hongxia, Zhang, Erbao, Zhang, Chang, Sun, Qi, Wang, Tingting, Ge, Yizhi, Zong, Dan, Chen, Wei, He, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474317/
https://www.ncbi.nlm.nih.gov/pubmed/37658588
http://dx.doi.org/10.1002/ctm2.1361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474317/
https://www.ncbi.nlm.nih.gov/pubmed/37658588
http://dx.doi.org/10.1002/ctm2.1361

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