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Where next for partial randomisation of research funding? The feasibility of RCTs and alternatives

We outline essential considerations for any study of partial randomisation of research funding, and consider scenarios in which randomised controlled trials (RCTs) would be feasible and appropriate. We highlight the interdependence of target outcomes, sample availability and statistical power for de...

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Detalles Bibliográficos
Autores principales: Stafford, Tom, Rombach, Ines, Hind, Dan, Mateen, Bilal, Woods, Helen Buckley, Dimario, Munya, Wilsdon, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474338/
https://www.ncbi.nlm.nih.gov/pubmed/37663796
http://dx.doi.org/10.12688/wellcomeopenres.19565.1
Descripción
Sumario:We outline essential considerations for any study of partial randomisation of research funding, and consider scenarios in which randomised controlled trials (RCTs) would be feasible and appropriate. We highlight the interdependence of target outcomes, sample availability and statistical power for determining the cost and feasibility of a trial. For many choices of target outcome, RCTs may be less practical and more expensive than they at first appear (in large part due to issues pertaining to sample size and statistical power). As such, we briefly discuss alternatives to RCTs. It is worth noting that many of the considerations relevant to experiments on partial randomisation may also apply to other potential experiments on funding processes (as described in The Experimental Research Funder’s Handbook. RoRI, June 2022).