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Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study
AIM: To compare the efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) (GC Tooth Mousse) and tricalcium phosphate formulation (Clinpro) by topical application and iontophoresis. BACKGROUND: Noninvasive treatment of dental caries is a major advance in the clinical management of t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Jaypee Brothers Medical Publishers
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474384/ https://www.ncbi.nlm.nih.gov/pubmed/37663207 http://dx.doi.org/10.5005/jp-journals-10005-2625 |
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author | Rebecca, VC Muppa, Radhika Nallanchakrava, Srinivas Togaru, Harshini Mutt, Niharika H Tangella, Aditya |
author_facet | Rebecca, VC Muppa, Radhika Nallanchakrava, Srinivas Togaru, Harshini Mutt, Niharika H Tangella, Aditya |
author_sort | Rebecca, VC |
collection | PubMed |
description | AIM: To compare the efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) (GC Tooth Mousse) and tricalcium phosphate formulation (Clinpro) by topical application and iontophoresis. BACKGROUND: Noninvasive treatment of dental caries is a major advance in the clinical management of the disease. MATERIALS AND METHODS: A total of 20 primary anterior and 20 primary molars were included in the study to be analyzed by transverse microradiography (TMR) and polarized light microscopy (PLM). The samples were coated with acid-resistant varnish, leaving a window on the buccal/lingual surface of enamel and immersed in demineralizing solution for 96 hours. Each sample was coated with varnish on the left half (control), and the right half served as a test. All the samples were divided into four groups. The test windows of specimens in groups I (GC Tooth Mousse) and II (Clinpro) were subjected to remineralization treatments for 10 days. Similarly, groups III and IV were subjected to iontophoresis using GC Tooth Mousse and Clinpro for 7 minutes. The samples were analyzed by TMR and PLM. RESULTS: There was no significant difference in the mean difference of mineral loss among the four groups. There was a significant difference in the mean difference of lesion depth among the four groups. CONCLUSION: Both iontophoresis and topical application were equally efficient, but one remineralization by iontophoresis equals 10 topical applications. HOW TO CITE THIS ARTICLE: VC R, Muppa R, Nallanchakrava S, et al. Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study. Int J Clin Pediatr Dent 2023;16(S-1):S85–S90. |
format | Online Article Text |
id | pubmed-10474384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Jaypee Brothers Medical Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-104743842023-09-03 Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study Rebecca, VC Muppa, Radhika Nallanchakrava, Srinivas Togaru, Harshini Mutt, Niharika H Tangella, Aditya Int J Clin Pediatr Dent Original Research AIM: To compare the efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) (GC Tooth Mousse) and tricalcium phosphate formulation (Clinpro) by topical application and iontophoresis. BACKGROUND: Noninvasive treatment of dental caries is a major advance in the clinical management of the disease. MATERIALS AND METHODS: A total of 20 primary anterior and 20 primary molars were included in the study to be analyzed by transverse microradiography (TMR) and polarized light microscopy (PLM). The samples were coated with acid-resistant varnish, leaving a window on the buccal/lingual surface of enamel and immersed in demineralizing solution for 96 hours. Each sample was coated with varnish on the left half (control), and the right half served as a test. All the samples were divided into four groups. The test windows of specimens in groups I (GC Tooth Mousse) and II (Clinpro) were subjected to remineralization treatments for 10 days. Similarly, groups III and IV were subjected to iontophoresis using GC Tooth Mousse and Clinpro for 7 minutes. The samples were analyzed by TMR and PLM. RESULTS: There was no significant difference in the mean difference of mineral loss among the four groups. There was a significant difference in the mean difference of lesion depth among the four groups. CONCLUSION: Both iontophoresis and topical application were equally efficient, but one remineralization by iontophoresis equals 10 topical applications. HOW TO CITE THIS ARTICLE: VC R, Muppa R, Nallanchakrava S, et al. Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study. Int J Clin Pediatr Dent 2023;16(S-1):S85–S90. Jaypee Brothers Medical Publishers 2023-08 /pmc/articles/PMC10474384/ /pubmed/37663207 http://dx.doi.org/10.5005/jp-journals-10005-2625 Text en Copyright © 2023; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2023 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Original Research Rebecca, VC Muppa, Radhika Nallanchakrava, Srinivas Togaru, Harshini Mutt, Niharika H Tangella, Aditya Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study |
title | Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study |
title_full | Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study |
title_fullStr | Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study |
title_full_unstemmed | Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study |
title_short | Evaluation of Iontophoresis as a Tool in Comparison to Topical Remineralization Systems by Transverse Microradiography and Polarized Light Microscopy: An In Vitro Study |
title_sort | evaluation of iontophoresis as a tool in comparison to topical remineralization systems by transverse microradiography and polarized light microscopy: an in vitro study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474384/ https://www.ncbi.nlm.nih.gov/pubmed/37663207 http://dx.doi.org/10.5005/jp-journals-10005-2625 |
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