Multimodal imaging study of the 5-HT(1A) receptor biased agonist, NLX-112, in a model of L-DOPA-induced dyskinesia

INTRODUCTION: The leading treatment for motor signs of Parkinson's disease is L-DOPA, but, upon extended use, it can lead to levodopa-induced dyskinesia (LID). Serotonergic neurons are involved in LID etiology and previous pre-clinical studies have shown that NLX-112, a 5-HT(1A) biased agonist,...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaib, Sarah, Vidal, Benjamin, Bouillot, Caroline, Depoortere, Ronan, Newman-Tancredi, Adrian, Zimmer, Luc, Levigoureux, Elise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474496/
https://www.ncbi.nlm.nih.gov/pubmed/37632990
http://dx.doi.org/10.1016/j.nicl.2023.103497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474496/
https://www.ncbi.nlm.nih.gov/pubmed/37632990
http://dx.doi.org/10.1016/j.nicl.2023.103497

Ejemplares similares