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Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia

BACKGROUND: Children with severe acute malnutrition (SAM) without complication are treated in the outpatient therapeutic program (OTP) and the program has been reported to be effective. However, relapse post-discharge from the program is poorly defined, and scarcely evaluated across programs and res...

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Autores principales: Teshale, Endalkachew Befekadu, Nigatu, Yakob Desalegn, Delbiso, Tefera Darge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474695/
https://www.ncbi.nlm.nih.gov/pubmed/37659998
http://dx.doi.org/10.1186/s12887-023-04269-7
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author Teshale, Endalkachew Befekadu
Nigatu, Yakob Desalegn
Delbiso, Tefera Darge
author_facet Teshale, Endalkachew Befekadu
Nigatu, Yakob Desalegn
Delbiso, Tefera Darge
author_sort Teshale, Endalkachew Befekadu
collection PubMed
description BACKGROUND: Children with severe acute malnutrition (SAM) without complication are treated in the outpatient therapeutic program (OTP) and the program has been reported to be effective. However, relapse post-discharge from the program is poorly defined, and scarcely evaluated across programs and research. The objective of this study is to assess the prevalence of SAM among children post-discharge from the OTP and to identify factors associated with SAM relapse in Gambella Region, Western Ethiopia. METHODS: We conducted a facility-based cross-sectional study among 208 children aged 6–59 months who have been discharged from the OTP as cured. Baseline data were collected from caregivers using structured questionnaire. Child anthropometry and oedema was measured. The association between SAM relapse and the risk factors were assessed using bivariate and multivariable logistic regression models. RESULTS: The prevalence of SAM relapse was 10.1% (95% CI: 5.8–14.0%). The odds of SAM relapse was significantly higher in children with mothers who had no exposure to education and promotion about infant and young child feeding (IYCF) practices (OR = 5.7; 95% CI: 1.3–12.6), children who were not fully immunized for their age (OR = 8.0; 95% CI: 3.8–23.4), and children with mid-upper arm circumference (MUAC) at discharge of < 12.5 cm (OR = 4.4; 95% CI: 2.1–12.8) than their counterparts. CONCLUSIONS: To reduce SAM relapse, the OTP programs should avoid premature discharge and consider provision of supplementary food for children with low MUAC at discharge. Further, the OTP discharge criteria should consider both the anthropometric indicators – weight-for-height/length z-score (WHZ) and MUAC – and the absence of bilateral pitting oedema irrespective of the anthropometric indicator that is used during admission. Promotion of nutrition education and improving child immunization services and coverage would help reduce SAM relapse. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-023-04269-7.
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spelling pubmed-104746952023-09-03 Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia Teshale, Endalkachew Befekadu Nigatu, Yakob Desalegn Delbiso, Tefera Darge BMC Pediatr Research BACKGROUND: Children with severe acute malnutrition (SAM) without complication are treated in the outpatient therapeutic program (OTP) and the program has been reported to be effective. However, relapse post-discharge from the program is poorly defined, and scarcely evaluated across programs and research. The objective of this study is to assess the prevalence of SAM among children post-discharge from the OTP and to identify factors associated with SAM relapse in Gambella Region, Western Ethiopia. METHODS: We conducted a facility-based cross-sectional study among 208 children aged 6–59 months who have been discharged from the OTP as cured. Baseline data were collected from caregivers using structured questionnaire. Child anthropometry and oedema was measured. The association between SAM relapse and the risk factors were assessed using bivariate and multivariable logistic regression models. RESULTS: The prevalence of SAM relapse was 10.1% (95% CI: 5.8–14.0%). The odds of SAM relapse was significantly higher in children with mothers who had no exposure to education and promotion about infant and young child feeding (IYCF) practices (OR = 5.7; 95% CI: 1.3–12.6), children who were not fully immunized for their age (OR = 8.0; 95% CI: 3.8–23.4), and children with mid-upper arm circumference (MUAC) at discharge of < 12.5 cm (OR = 4.4; 95% CI: 2.1–12.8) than their counterparts. CONCLUSIONS: To reduce SAM relapse, the OTP programs should avoid premature discharge and consider provision of supplementary food for children with low MUAC at discharge. Further, the OTP discharge criteria should consider both the anthropometric indicators – weight-for-height/length z-score (WHZ) and MUAC – and the absence of bilateral pitting oedema irrespective of the anthropometric indicator that is used during admission. Promotion of nutrition education and improving child immunization services and coverage would help reduce SAM relapse. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-023-04269-7. BioMed Central 2023-09-02 /pmc/articles/PMC10474695/ /pubmed/37659998 http://dx.doi.org/10.1186/s12887-023-04269-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Teshale, Endalkachew Befekadu
Nigatu, Yakob Desalegn
Delbiso, Tefera Darge
Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia
title Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia
title_full Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia
title_fullStr Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia
title_full_unstemmed Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia
title_short Relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western Ethiopia
title_sort relapse of severe acute malnutrition among children discharged from outpatient therapeutic program in western ethiopia
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474695/
https://www.ncbi.nlm.nih.gov/pubmed/37659998
http://dx.doi.org/10.1186/s12887-023-04269-7
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