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Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery

BACKGROUND: Surgical prophylaxis for venous thrombo-embolic disease (VTE) includes risk assessment, chemical prophylaxis and mechanical prophylaxis (graduated compression stockings [GCS] and/or intermittent pneumatic compression devices [IPCD]). Although there is overwhelming evidence for the need a...

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Autores principales: Lott, Natalie, Senanayake, Tharindu, Carroll, Rosemary, Gani, Jon, Smith, Stephen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474754/
https://www.ncbi.nlm.nih.gov/pubmed/37658331
http://dx.doi.org/10.1186/s12893-023-02135-y
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author Lott, Natalie
Senanayake, Tharindu
Carroll, Rosemary
Gani, Jon
Smith, Stephen R
author_facet Lott, Natalie
Senanayake, Tharindu
Carroll, Rosemary
Gani, Jon
Smith, Stephen R
author_sort Lott, Natalie
collection PubMed
description BACKGROUND: Surgical prophylaxis for venous thrombo-embolic disease (VTE) includes risk assessment, chemical prophylaxis and mechanical prophylaxis (graduated compression stockings [GCS] and/or intermittent pneumatic compression devices [IPCD]). Although there is overwhelming evidence for the need and efficacy of VTE prophylaxis in patients at risk, only about a third of those who are at risk of VTE receive appropriate prophylaxis. OBJECTIVE: There is debate as to the best combination of VTE prophylaxis following abdominal surgery due to lack of evidence. The aim of this survey was to understand this gap between knowledge and practice. METHODS: In 2019 and 2020, a survey was conducted to investigate the current practice of venous thromboembolism (VTE) prophylaxis for major abdominal surgery, with a focus on colorectal resections. The study received ethics approval and involved distributing an 11-item questionnaire to members of two professional surgical societies: the Colorectal Surgical Society of Australia and New Zealand (CSSANZ) and the General Surgeons Australia (GSA). RESULTS: From 214 surgeons: 100% use chemical prophylaxis, 68% do not use a risk assessment tool, 27% do not vary practice according to patient risk factors while > 90% use all three forms of VTE prophylaxis at some stage of treatment. Most surgeons do not vary practice between laparoscopic and open colectomy/major abdominal surgery and only 33% prescribe post-discharge chemical prophylaxis. 42% of surgeons surveyed had equipoise for a clinical trial on the use of IPCDs and the vast majority (> 95%) feel that IPCDs should provide at least a 2% improvement in VTE event rate in order to justify their routine use. CONCLUSION: Most surgeons in Australia and New Zealand do not use risk assessment tools and use all three forms of prophylaxis regardless. Therfore there is a gap between practice and VTE prophylaxis for the use of mechanical prophylaxis options. Further research is required to determine whether dual modality mechanical prophylaxis is incrementally efficacious. Trial Registration- Not Applicable. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12893-023-02135-y.
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spelling pubmed-104747542023-09-03 Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery Lott, Natalie Senanayake, Tharindu Carroll, Rosemary Gani, Jon Smith, Stephen R BMC Surg Research BACKGROUND: Surgical prophylaxis for venous thrombo-embolic disease (VTE) includes risk assessment, chemical prophylaxis and mechanical prophylaxis (graduated compression stockings [GCS] and/or intermittent pneumatic compression devices [IPCD]). Although there is overwhelming evidence for the need and efficacy of VTE prophylaxis in patients at risk, only about a third of those who are at risk of VTE receive appropriate prophylaxis. OBJECTIVE: There is debate as to the best combination of VTE prophylaxis following abdominal surgery due to lack of evidence. The aim of this survey was to understand this gap between knowledge and practice. METHODS: In 2019 and 2020, a survey was conducted to investigate the current practice of venous thromboembolism (VTE) prophylaxis for major abdominal surgery, with a focus on colorectal resections. The study received ethics approval and involved distributing an 11-item questionnaire to members of two professional surgical societies: the Colorectal Surgical Society of Australia and New Zealand (CSSANZ) and the General Surgeons Australia (GSA). RESULTS: From 214 surgeons: 100% use chemical prophylaxis, 68% do not use a risk assessment tool, 27% do not vary practice according to patient risk factors while > 90% use all three forms of VTE prophylaxis at some stage of treatment. Most surgeons do not vary practice between laparoscopic and open colectomy/major abdominal surgery and only 33% prescribe post-discharge chemical prophylaxis. 42% of surgeons surveyed had equipoise for a clinical trial on the use of IPCDs and the vast majority (> 95%) feel that IPCDs should provide at least a 2% improvement in VTE event rate in order to justify their routine use. CONCLUSION: Most surgeons in Australia and New Zealand do not use risk assessment tools and use all three forms of prophylaxis regardless. Therfore there is a gap between practice and VTE prophylaxis for the use of mechanical prophylaxis options. Further research is required to determine whether dual modality mechanical prophylaxis is incrementally efficacious. Trial Registration- Not Applicable. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12893-023-02135-y. BioMed Central 2023-09-01 /pmc/articles/PMC10474754/ /pubmed/37658331 http://dx.doi.org/10.1186/s12893-023-02135-y Text en © Crown 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Lott, Natalie
Senanayake, Tharindu
Carroll, Rosemary
Gani, Jon
Smith, Stephen R
Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery
title Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery
title_full Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery
title_fullStr Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery
title_full_unstemmed Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery
title_short Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery
title_sort venous thromboembolic prophylaxis: current practice of surgeons in australia and new zealand for major abdominal surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474754/
https://www.ncbi.nlm.nih.gov/pubmed/37658331
http://dx.doi.org/10.1186/s12893-023-02135-y
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