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Mini-dose methotrexate combined with methylprednisolone as a first-line treatment for acute graft-versus-host disease: A phase 2 trial

BACKGROUND AND OBJECTIVES: Acute graft-versus-host disease (aGvHD) remains a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methylprednisolone (MP; 1–2 mg/kg/day) remains the standard first-line therapy for aGvHD, although no response is detected in nearly o...

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Detalles Bibliográficos
Autores principales: Xu, Zhengli, Mo, Xiaodong, Kong, Yuan, Wen, Qi, Han, Tingting, Lyu, Meng, Xu, Lanping, Chang, Yingjun, Zhang, Xiaohui, Huang, Xiaojun, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474881/
https://www.ncbi.nlm.nih.gov/pubmed/37662885
http://dx.doi.org/10.2478/jtim-2023-0111