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Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature

Patients with thrombocytopenia may report easy bruising, abnormal bleeding, and fatigue. Drug-induced thrombocytopenia has been reported with a variety of medications, most commonly heparin products, sulphonamides, carbamazepine, nonsteroidal anti-inflammatory drugs, anti-epileptic drugs, and chemot...

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Detalles Bibliográficos
Autores principales: Zhou, Allen, Sandhu, Michael, Min, Brian, Habib, Gaston, Gutsche, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474947/
https://www.ncbi.nlm.nih.gov/pubmed/37664297
http://dx.doi.org/10.7759/cureus.42918
Descripción
Sumario:Patients with thrombocytopenia may report easy bruising, abnormal bleeding, and fatigue. Drug-induced thrombocytopenia has been reported with a variety of medications, most commonly heparin products, sulphonamides, carbamazepine, nonsteroidal anti-inflammatory drugs, anti-epileptic drugs, and chemotherapy. We present the case of a 58-year-old female with severe thrombocytopenia attributed to a calcium channel blocker (CCB) overdose, a very rare cause of thrombocytopenia. We discuss the diagnostic work-up and management in the intensive care unit and perform a literature review.