Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature

Patients with thrombocytopenia may report easy bruising, abnormal bleeding, and fatigue. Drug-induced thrombocytopenia has been reported with a variety of medications, most commonly heparin products, sulphonamides, carbamazepine, nonsteroidal anti-inflammatory drugs, anti-epileptic drugs, and chemot...

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Detalles Bibliográficos
Autores principales: Zhou, Allen, Sandhu, Michael, Min, Brian, Habib, Gaston, Gutsche, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474947/
https://www.ncbi.nlm.nih.gov/pubmed/37664297
http://dx.doi.org/10.7759/cureus.42918
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author Zhou, Allen
Sandhu, Michael
Min, Brian
Habib, Gaston
Gutsche, Markus
author_facet Zhou, Allen
Sandhu, Michael
Min, Brian
Habib, Gaston
Gutsche, Markus
author_sort Zhou, Allen
collection PubMed
description Patients with thrombocytopenia may report easy bruising, abnormal bleeding, and fatigue. Drug-induced thrombocytopenia has been reported with a variety of medications, most commonly heparin products, sulphonamides, carbamazepine, nonsteroidal anti-inflammatory drugs, anti-epileptic drugs, and chemotherapy. We present the case of a 58-year-old female with severe thrombocytopenia attributed to a calcium channel blocker (CCB) overdose, a very rare cause of thrombocytopenia. We discuss the diagnostic work-up and management in the intensive care unit and perform a literature review.
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spelling pubmed-104749472023-09-03 Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature Zhou, Allen Sandhu, Michael Min, Brian Habib, Gaston Gutsche, Markus Cureus Internal Medicine Patients with thrombocytopenia may report easy bruising, abnormal bleeding, and fatigue. Drug-induced thrombocytopenia has been reported with a variety of medications, most commonly heparin products, sulphonamides, carbamazepine, nonsteroidal anti-inflammatory drugs, anti-epileptic drugs, and chemotherapy. We present the case of a 58-year-old female with severe thrombocytopenia attributed to a calcium channel blocker (CCB) overdose, a very rare cause of thrombocytopenia. We discuss the diagnostic work-up and management in the intensive care unit and perform a literature review. Cureus 2023-08-03 /pmc/articles/PMC10474947/ /pubmed/37664297 http://dx.doi.org/10.7759/cureus.42918 Text en Copyright © 2023, Zhou et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Zhou, Allen
Sandhu, Michael
Min, Brian
Habib, Gaston
Gutsche, Markus
Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature
title Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature
title_full Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature
title_fullStr Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature
title_full_unstemmed Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature
title_short Calcium Channel Blocker-Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature
title_sort calcium channel blocker-induced thrombocytopenia in the intensive care unit: a rare presentation and review of the literature
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474947/
https://www.ncbi.nlm.nih.gov/pubmed/37664297
http://dx.doi.org/10.7759/cureus.42918
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