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FUS-ERG induces late-onset azacitidine resistance in acute myeloid leukaemia cells

FUS-ERG is a chimeric gene with a poor prognosis, found in myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML). It remains unclear whether DNA hypomethylating agents, including azacitidine (Aza), are effective in FUS-ERG-harbouring AML and how FUS-ERG induces chemoresistance. Stable Ba...

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Detalles Bibliográficos
Autores principales:	Asai-Nishishita, Ai, Kawahara, Masahiro, Tatsumi, Goichi, Iwasa, Masaki, Fujishiro, Aya, Nishimura, Rie, Minamiguchi, Hitoshi, Kito, Katsuyuki, Murata, Makoto, Andoh, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475016/ https://www.ncbi.nlm.nih.gov/pubmed/37660196 http://dx.doi.org/10.1038/s41598-023-41230-1

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