Substituted salicylic acid analogs offer improved potency against multidrug-resistant Neisseria gonorrhoeae and good selectivity against commensal vaginal bacteria

Drug-resistant Neisseria gonorrhoeae represents a major threat to public health; without new effective antibiotics, untreatable gonococcal infections loom as a real possibility. In a previous drug-repurposing study, we reported that salicylic acid had good potency against azithromycin-resistant N. g...

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Detalles Bibliográficos
Autores principales: Almolhim, Hanan, Elhassanny, Ahmed E. M., Abutaleb, Nader S., Abdelsattar, Abdallah S., Seleem, Mohamed N., Carlier, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475031/
https://www.ncbi.nlm.nih.gov/pubmed/37660222
http://dx.doi.org/10.1038/s41598-023-41442-5

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