Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths

Ascl1 and Ngn2, closely related proneural transcription factors, are able to convert mouse embryonic stem cells into induced neurons. Despite their similarities, these factors elicit only partially overlapping transcriptional programs, and it remains unknown whether cells are converted via distinct...

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Detalles Bibliográficos
Autores principales: Vainorius, Gintautas, Novatchkova, Maria, Michlits, Georg, Baar, Juliane Christina, Raupach, Cecilia, Lee, Joonsun, Yelagandula, Ramesh, Wernig, Marius, Elling, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475046/
https://www.ncbi.nlm.nih.gov/pubmed/37660160
http://dx.doi.org/10.1038/s41467-023-40803-y

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