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Reversible suppression of circadian-driven locomotor rhythms in mice using a gradual fragmentation of the day-night cycle
Circadian rhythms are regulated by molecular clockwork and drive 24-h behaviors such as locomotor activity, which can be rendered non-functional through genetic knockouts of clock genes. Circadian rhythms are robust in constant darkness (DD) but are modulated to become exactly 24 h by the external d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475134/ https://www.ncbi.nlm.nih.gov/pubmed/37660212 http://dx.doi.org/10.1038/s41598-023-41029-0 |