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Understandings, attitudes, practices and responses to GHB overdose among GHB consumers

BACKGROUND: Gamma-hydroxybutyrate (GHB) is used at disproportionately high rates within sexuality and gender diverse communities and carries a high risk of overdose. GHB overdose can result in death. Internationally, recent increases in GHB overdoses have been observed. Coronial reviews of GHB-relat...

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Autores principales: Freestone, Jack, Ezard, Nadine, Bourne, Adam, Brett, Jonathan, Roberts, Darren M., Hammoud, Mohamed, Nedanoski, Anthony, Prestage, Garrett, Siefried, Krista J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475182/
https://www.ncbi.nlm.nih.gov/pubmed/37660058
http://dx.doi.org/10.1186/s12954-023-00857-z
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author Freestone, Jack
Ezard, Nadine
Bourne, Adam
Brett, Jonathan
Roberts, Darren M.
Hammoud, Mohamed
Nedanoski, Anthony
Prestage, Garrett
Siefried, Krista J.
author_facet Freestone, Jack
Ezard, Nadine
Bourne, Adam
Brett, Jonathan
Roberts, Darren M.
Hammoud, Mohamed
Nedanoski, Anthony
Prestage, Garrett
Siefried, Krista J.
author_sort Freestone, Jack
collection PubMed
description BACKGROUND: Gamma-hydroxybutyrate (GHB) is used at disproportionately high rates within sexuality and gender diverse communities and carries a high risk of overdose. GHB overdose can result in death. Internationally, recent increases in GHB overdoses have been observed. Coronial reviews of GHB-related death highlight the pivotal roles that bystanders to GHB overdose play in preventing fatality. No research has examined, in detail, how bystanders respond to GHB overdose. This qualitative study was conducted among people who use GHB and explored how they responded upon witnessing a GHB overdose experienced by someone else. METHODS: Interviews were conducted with 31 sexuality and gender diverse Australian residents reporting three or more occasions of GHB use in the previous 12 months. Participants were asked questions about witnessed GHB overdose, their actions and decision-making processes throughout overdose. Data were analysed thematically. RESULTS: Participants described witnessing GHB overdose, commonly in private settings involving sexualized GHB use. Variable definitions of GHB overdose were reported, ranging from GHB-induced symptoms of distress to comatose intoxication. Drastic actions to keep someone alert and responsive post-GHB ingestion were reported; these included the administration of stimulant substances and citrus. Decisions to call or not call for emergency medical services (EMS) were influenced by many circumstantial variables. In most instances, an EMS call was resisted and response practices deviated from established first aid protocols. CONCLUSIONS: GHB overdose prevention and response training programs targeting people who use GHB are urgently required. These education interventions ought to address inaccuracies that inform street remedies for GHB overdose, teach people how to safely check breathing and response, promote basic first aid principles and address barriers to contacting EMS.
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spelling pubmed-104751822023-09-04 Understandings, attitudes, practices and responses to GHB overdose among GHB consumers Freestone, Jack Ezard, Nadine Bourne, Adam Brett, Jonathan Roberts, Darren M. Hammoud, Mohamed Nedanoski, Anthony Prestage, Garrett Siefried, Krista J. Harm Reduct J Research BACKGROUND: Gamma-hydroxybutyrate (GHB) is used at disproportionately high rates within sexuality and gender diverse communities and carries a high risk of overdose. GHB overdose can result in death. Internationally, recent increases in GHB overdoses have been observed. Coronial reviews of GHB-related death highlight the pivotal roles that bystanders to GHB overdose play in preventing fatality. No research has examined, in detail, how bystanders respond to GHB overdose. This qualitative study was conducted among people who use GHB and explored how they responded upon witnessing a GHB overdose experienced by someone else. METHODS: Interviews were conducted with 31 sexuality and gender diverse Australian residents reporting three or more occasions of GHB use in the previous 12 months. Participants were asked questions about witnessed GHB overdose, their actions and decision-making processes throughout overdose. Data were analysed thematically. RESULTS: Participants described witnessing GHB overdose, commonly in private settings involving sexualized GHB use. Variable definitions of GHB overdose were reported, ranging from GHB-induced symptoms of distress to comatose intoxication. Drastic actions to keep someone alert and responsive post-GHB ingestion were reported; these included the administration of stimulant substances and citrus. Decisions to call or not call for emergency medical services (EMS) were influenced by many circumstantial variables. In most instances, an EMS call was resisted and response practices deviated from established first aid protocols. CONCLUSIONS: GHB overdose prevention and response training programs targeting people who use GHB are urgently required. These education interventions ought to address inaccuracies that inform street remedies for GHB overdose, teach people how to safely check breathing and response, promote basic first aid principles and address barriers to contacting EMS. BioMed Central 2023-09-02 /pmc/articles/PMC10475182/ /pubmed/37660058 http://dx.doi.org/10.1186/s12954-023-00857-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Freestone, Jack
Ezard, Nadine
Bourne, Adam
Brett, Jonathan
Roberts, Darren M.
Hammoud, Mohamed
Nedanoski, Anthony
Prestage, Garrett
Siefried, Krista J.
Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
title Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
title_full Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
title_fullStr Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
title_full_unstemmed Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
title_short Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
title_sort understandings, attitudes, practices and responses to ghb overdose among ghb consumers
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475182/
https://www.ncbi.nlm.nih.gov/pubmed/37660058
http://dx.doi.org/10.1186/s12954-023-00857-z
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