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Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma

BACKGROUND: Progranulin (PGRN), a glycoprotein secreted by a wide range of epithelial cells and plays an important role in inflammatory mechanisms and tumor progression. In this study, the expression, and functions of PGRN in papillary thyroid carcinoma (PTC) was examined to explore the potential pa...

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Detalles Bibliográficos
Autores principales: Dong, Yanxu, Tan, Hao, Wang, Lidong, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475200/
https://www.ncbi.nlm.nih.gov/pubmed/37660003
http://dx.doi.org/10.1186/s12935-023-03033-2