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Reduced Plasticity in Coupling Strength in the Aging SCN Clock as Revealed by Kuramoto Modeling
The mammalian circadian clock is located in the suprachiasmatic nucleus (SCN) and consists of a network of coupled neurons, which are entrained to the environmental light-dark cycle. The phase coherence of the neurons is plastic and driven by the duration of daylight. With aging, the capacity to beh...
Autores principales: | van Beurden, Anouk W., Meylahn, Janusz M., Achterhof, Stefan, Buijink, Renate, Olde Engberink, Anneke, Michel, Stephan, Meijer, Johanna H., Rohling, Jos H. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475211/ https://www.ncbi.nlm.nih.gov/pubmed/37329153 http://dx.doi.org/10.1177/07487304231175191 |
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