Cargando…

Novel Curcumin Analogue L6H4 in Treating Liver Fibrosis and Type 2 Diabetes

PURPOSE: The objective of this study was to evaluate the therapeutic efficacy of the curcumin analogue L6H4 in attenuating liver fibrosis and alleviating insulin resistance in streptozotocin-induced diabetic rats. METHODS: Male Sprague-Dawley rats were fed a high-fat diet to induce insulin resistanc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Jun, Vaishnani, Deep K, Mansi, Zeng, Jing, Xie, Zhenwen, Jin, Xuanchen, Zhang, Haixia, Wut Yi Hla, Khaing, Ying, Furong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475286/ https://www.ncbi.nlm.nih.gov/pubmed/37667770 http://dx.doi.org/10.2147/DMSO.S425038

Ejemplares similares

Curcumin in Health and Diseases: Alzheimer’s Disease and Curcumin Analogues, Derivatives, and Hybrids
por: Chainoglou, Eirini, et al.
Publicado: (2020)

Recent Advances of Curcumin in the Prevention and Treatment of Renal Fibrosis
por: Sun, Xuejiao, et al.
Publicado: (2017)

Molecular docking analysis of curcumin analogues with COX-2
por: Sohilait, Mario Rowan, et al.
Publicado: (2017)

Molecular Pathways Modulated by Curcumin Analogue, Diarylpentanoids in Cancer
por: Paulraj, Felicia, et al.
Publicado: (2019)

Application of artificial neural networks in detection and diagnosis of gastrointestinal and liver tumors
por: Mao, Wei-Bo, et al.
Publicado: (2020)

Computational elucidation of the binding mechanisms of curcumin analogues as bacterial RecA inhibitors
por: Zhou, Zi-Yuan, et al.
Publicado: (2019)

Antidiabetic Potential of the Heme Oxygenase-1 Inducer Curcumin Analogues
por: Son, Yong, et al.
Publicado: (2013)

Synthesis and Biological Evaluation of Unsymmetrical Curcumin Analogues as Tyrosinase Inhibitors
por: Jiang, Yongfu, et al.
Publicado: (2013)

Curcumin–Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders
por: Quezada, Elías, et al.
Publicado: (2021)

An insight into the in vivo imaging potential of curcumin analogues as fluorescence probes
por: Liu, Yu, et al.
Publicado: (2021)

Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy
por: Ramasamy, Thamil Selvee, et al.
Publicado: (2015)

Anti-liver fibrosis activity of curcumin/chitosan-coated green silver nanoparticles
por: Elzoheiry, Alya, et al.
Publicado: (2022)

Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase
por: Kim, Bo Ram, et al.
Publicado: (2018)

The Anti-Cancer Effect of Four Curcumin Analogues on Human Glioma Cells
por: Luo, Siou-Min, et al.
Publicado: (2021)

Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells
por: Zhang, Feng, et al.
Publicado: (2014)

Drug holiday in patients with polycystic liver disease treated with somatostatin analogues
por: van Aerts, René M. M., et al.
Publicado: (2018)

Molecular changes induced by the curcumin analogue D6 in human melanoma cells
por: Rozzo, Carla, et al.
Publicado: (2013)

Folate Decorated Nanomicelles Loaded with a Potent Curcumin Analogue for Targeting Retinoblastoma
por: Alsaab, Hashem, et al.
Publicado: (2017)

Investigation of Antistress and Antidepressant Activities of Synthetic Curcumin Analogues: Behavioral and Biomarker Approach
por: Hussain, Haya, et al.
Publicado: (2022)

Synthetic Mono-Carbonyl Curcumin Analogues Attenuate Oxidative Stress in Mouse Models
por: Hussain, Haya, et al.
Publicado: (2022)

The curcumin analogue PAC has potent anti-anaplastic thyroid cancer effects
por: Al-Mohanna, Mai, et al.
Publicado: (2023)

Synthesis, DFT Analyses, Antiproliferative Activity, and Molecular Docking Studies of Curcumin Analogues
por: Ahsan, Mohamed Jawed, et al.
Publicado: (2022)

Synthesis, Biological Evaluation, and Molecular Modeling Studies of 1-Aryl-1H-pyrazole-Fused Curcumin Analogues as Anticancer Agents
por: Doan, Nam Q. H., et al.
Publicado: (2022)

Artificial intelligence in bladder cancer: current trends and future possibilities
por: Ma, Jun, et al.
Publicado: (2022)

Curcumin analogues as selective fluorescence imaging probes for brown adipose tissue and monitoring browning
por: Zhang, Xueli, et al.
Publicado: (2015)

Inhibition of LPS-induced production of inflammatory factors in the macrophages by mono-carbonyl analogues of curcumin
por: Liang, Guang, et al.
Publicado: (2009)

Inhibition of the NF-κB Signaling Pathway by a Novel Heterocyclic Curcumin Analogue
por: Katsori, Anna-Maria, et al.
Publicado: (2015)

Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues
por: De Lorenzi, Ersilia, et al.
Publicado: (2022)

Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection
por: Richart, Sarah M., et al.
Publicado: (2018)

PEMPHIGUS: ACTIVE OR INACTIVE?
por: Vaishnani, Jignesh B, et al.
Publicado: (2009)

The role of curcumin in liver diseases
por: Buonomo, Antonio Riccardo, et al.
Publicado: (2018)

Curcumin analogue BDDD-721 exhibits more potent anticancer effects than curcumin on medulloblastoma by targeting Shh/Gli1 signaling pathway
por: Gong, Weiyi, et al.
Publicado: (2022)

New evidence for the therapeutic potential of curcumin to treat nonalcoholic fatty liver disease in humans
por: Inzaugarat, María Eugenia, et al.
Publicado: (2017)

Biological Evaluation and 3D-QSAR Studies of Curcumin Analogues as Aldehyde Dehydrogenase 1 Inhibitors
por: Wang, Hui, et al.
Publicado: (2014)

Potential Application of Curcumin and Its Analogues in the Treatment Strategy of Patients with Primary Epithelial Ovarian Cancer
por: Terlikowska, Katarzyna M., et al.
Publicado: (2014)

Effects of Curcumin Analogues DMC and EF24 in Combination with the Cytokine TRAIL against Kidney Cancer
por: Ibáñez Gaspar, Verónica, et al.
Publicado: (2021)

Monocarbonyl Curcumin Analogues as Potent Inhibitors against Human Glutathione Transferase P1-1
por: Pantiora, Panagiota, et al.
Publicado: (2022)

Curcumin Suppresses Intestinal Fibrosis by Inhibition of PPARγ-Mediated Epithelial-Mesenchymal Transition
por: Xu, Su, et al.
Publicado: (2017)

Mitochondria-targeted curcumin loaded CTPP–PEG–PCL self-assembled micelles for improving liver fibrosis therapy
por: Zhang, Liqiao, et al.
Publicado: (2021)

Palladium-catalyzed C–H olefination of uridine, deoxyuridine, uridine monophosphate and uridine analogues
por: Zhao, Qin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tf707j0fqgc5caom5khp7dmqo6