Chidamide and Oxaliplatin Synergistically Inhibit Colorectal Cancer Growth by Regulating the RPS27A-MDM2-P53 Axis

PURPOSE: The present study explored the anti-tumor effects of chidamide plus oxaliplatin on colorectal cancer (CRC) and examined its underlying mechanism. MATERIAL AND METHODS: First, the Combination Index (CI) of chidamide and oxaliplatin was evaluated via CCK-8 assay. Second, the effects of chidam...

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Detalles Bibliográficos
Autores principales: Li, Zhaopeng, Bu, Deyong, Wang, Xiaobin, Zhu, Lin, Lei, Daoyan, Tang, Fengling, Sun, Xianghua, Chen, Cheng, Ji, Xiang, Bai, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475304/
https://www.ncbi.nlm.nih.gov/pubmed/37667747
http://dx.doi.org/10.2147/OTT.S416824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475304/
https://www.ncbi.nlm.nih.gov/pubmed/37667747
http://dx.doi.org/10.2147/OTT.S416824

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