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Five Reasons Why Some Herniated Intervertebral Discs are Painless
Herniated intervertebral discs (HIVDs) can cause lower back pain and leg pain, but not all cases are painful. We suggest five potential reasons for painless HIVDs. First, when inflammation resolves or is insufficient, pain may not occur. Second, rare cases exhibit motor or sensory deficits without p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475350/ https://www.ncbi.nlm.nih.gov/pubmed/37670737 http://dx.doi.org/10.2147/JPR.S424925 |
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author | Shin, Dong Ah Chang, Min Cheol |
author_facet | Shin, Dong Ah Chang, Min Cheol |
author_sort | Shin, Dong Ah |
collection | PubMed |
description | Herniated intervertebral discs (HIVDs) can cause lower back pain and leg pain, but not all cases are painful. We suggest five potential reasons for painless HIVDs. First, when inflammation resolves or is insufficient, pain may not occur. Second, rare cases exhibit motor or sensory deficits without pain, suggesting a mechanical rather than inflammatory component. Third, changes in gene expression within the dorsal root ganglia may prevent persistent inflammation and pain. Fourth, reorganization of neural circuits in the spinal dorsal horn can reduce nociceptive signals and lead to painlessness. Fifth, effective pain coping strategies and higher pain tolerance may mask any discomfort. Understanding these factors can improve clinicians’ knowledge and aid in pain management. |
format | Online Article Text |
id | pubmed-10475350 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-104753502023-09-05 Five Reasons Why Some Herniated Intervertebral Discs are Painless Shin, Dong Ah Chang, Min Cheol J Pain Res Commentary Herniated intervertebral discs (HIVDs) can cause lower back pain and leg pain, but not all cases are painful. We suggest five potential reasons for painless HIVDs. First, when inflammation resolves or is insufficient, pain may not occur. Second, rare cases exhibit motor or sensory deficits without pain, suggesting a mechanical rather than inflammatory component. Third, changes in gene expression within the dorsal root ganglia may prevent persistent inflammation and pain. Fourth, reorganization of neural circuits in the spinal dorsal horn can reduce nociceptive signals and lead to painlessness. Fifth, effective pain coping strategies and higher pain tolerance may mask any discomfort. Understanding these factors can improve clinicians’ knowledge and aid in pain management. Dove 2023-08-30 /pmc/articles/PMC10475350/ /pubmed/37670737 http://dx.doi.org/10.2147/JPR.S424925 Text en © 2023 Shin and Chang. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Commentary Shin, Dong Ah Chang, Min Cheol Five Reasons Why Some Herniated Intervertebral Discs are Painless |
title | Five Reasons Why Some Herniated Intervertebral Discs are Painless |
title_full | Five Reasons Why Some Herniated Intervertebral Discs are Painless |
title_fullStr | Five Reasons Why Some Herniated Intervertebral Discs are Painless |
title_full_unstemmed | Five Reasons Why Some Herniated Intervertebral Discs are Painless |
title_short | Five Reasons Why Some Herniated Intervertebral Discs are Painless |
title_sort | five reasons why some herniated intervertebral discs are painless |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475350/ https://www.ncbi.nlm.nih.gov/pubmed/37670737 http://dx.doi.org/10.2147/JPR.S424925 |
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