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Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism

Oral potentially malignant disorders (OPMDs) are precursors of oral squamous cell carcinoma (OSCC). Deregulated cellular energy metabolism is a critical hallmark of cancer cells. Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC1α) plays vital role in mitochondrial energy met...

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Detalles Bibliográficos
Autores principales:	Liu, Yunkun, Huang, Nengwen, Qiao, Xianghe, Gu, Zhiyu, Wu, Yongzhi, Li, Jinjin, Wu, Chengzhou, Li, Bo, Li, Longjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475463/ https://www.ncbi.nlm.nih.gov/pubmed/37661238 http://dx.doi.org/10.1038/s41368-023-00242-3

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