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Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in MEK/ERK‐dependent colorectal cancer

The bone morphogenetic protein (BMP) pathway promotes differentiation and induces apoptosis in normal colorectal epithelial cells. However, its role in colorectal cancer (CRC) is controversial, where it can act as context‐dependent tumor promoter or tumor suppressor. Here we have found that CRC cell...

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Detalles Bibliográficos
Autores principales: Shimizu, Shota, Kondo, Jumpei, Onuma, Kunishige, Coppo, Roberto, Ota, Kasumi, Kamada, Mayumi, Harada, Yohei, Tanaka, Yoshihisa, Nakazawa, Mai Adachi, Tamada, Yoshinori, Okuno, Yasushi, Kawada, Kenji, Obama, Kazutaka, Coffey, Robert J., Fujiwara, Yoshiyuki, Inoue, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475764/
https://www.ncbi.nlm.nih.gov/pubmed/37357017
http://dx.doi.org/10.1111/cas.15882

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