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Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in MEK/ERK‐dependent colorectal cancer
The bone morphogenetic protein (BMP) pathway promotes differentiation and induces apoptosis in normal colorectal epithelial cells. However, its role in colorectal cancer (CRC) is controversial, where it can act as context‐dependent tumor promoter or tumor suppressor. Here we have found that CRC cell...
Autores principales: | Shimizu, Shota, Kondo, Jumpei, Onuma, Kunishige, Coppo, Roberto, Ota, Kasumi, Kamada, Mayumi, Harada, Yohei, Tanaka, Yoshihisa, Nakazawa, Mai Adachi, Tamada, Yoshinori, Okuno, Yasushi, Kawada, Kenji, Obama, Kazutaka, Coffey, Robert J., Fujiwara, Yoshiyuki, Inoue, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475764/ https://www.ncbi.nlm.nih.gov/pubmed/37357017 http://dx.doi.org/10.1111/cas.15882 |
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