Targeting phosphomevalonate kinase enhances radiosensitivity via ubiquitination of the replication protein A1 in lung cancer cells

Radiotherapy (RT) plays an important role in localized lung cancer treatments. Although RT locally targets and controls malignant lesions, RT resistance prevents RT from being an effective treatment for lung cancer. In this study, we identified phosphomevalonate kinase (PMVK) as a novel radiosensiti...

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Detalles Bibliográficos
Autores principales: Park, Seok Soon, Kwon, Mi Ri, Ju, Eun Jin, Shin, Seol Hwa, Park, Jin, Ko, Eun Jung, Son, Ga Won, Lee, Hye Won, Kim, Yeon Joo, Moon, Gyeong Joon, Park, Yun‐Yong, Song, Si Yeol, Jeong, Seong‐Yun, Choi, Eun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475767/
https://www.ncbi.nlm.nih.gov/pubmed/37650703
http://dx.doi.org/10.1111/cas.15896

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