Pan-conserved segment tags identify ultra-conserved sequences across assemblies in the human pangenome

The human pangenome, a new reference sequence, addresses many limitations of the current GRCh38 reference. The first release is based on 94 high-quality haploid assemblies from individuals with diverse backgrounds. We employed a k-mer indexing strategy for comparative analysis across multiple assemb...

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Detalles Bibliográficos
Autores principales: Lee, HoJoon, Greer, Stephanie U., Pavlichin, Dmitri S., Zhou, Bo, Urban, Alexander E., Weissman, Tsachy, Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475782/
https://www.ncbi.nlm.nih.gov/pubmed/37671027
http://dx.doi.org/10.1016/j.crmeth.2023.100543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475782/
https://www.ncbi.nlm.nih.gov/pubmed/37671027
http://dx.doi.org/10.1016/j.crmeth.2023.100543

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