Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery

PURPOSE: C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC). METHODS: Three hundred twent...

Descripción completa

Detalles Bibliográficos
Autores principales: Kataoka, Masahiro, Gomi, Kuniyuki, Ichioka, Ken, Iguchi, Takuya, Shirota, Tomoki, Makino, Arano, Shimada, Ko, Maruyama, Kiyotomi, Mihara, Motohiro, Kajikawa, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Coloproctology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475807/
https://www.ncbi.nlm.nih.gov/pubmed/35692185
http://dx.doi.org/10.3393/ac.2022.00234.0033
Descripción
Sumario:PURPOSE: C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC). METHODS: Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (72 patients per group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching. RESULTS: The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed. CONCLUSION: In patients with CRC, CAR of POD 7 was a significant prognostic factor.

Ejemplares similares