Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast

Iwatsuki and colleagues have generated self-renewing pluripotent stem cells from the pre-gastrulation epiblast of the rat embryo and from other cellular sources: rat embryonic stem cells (rESCs) and epiblast-like cells derived from the rESCs. These rat epiblast-derived stem cells (rEpiSCs) display g...

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Detalles Bibliográficos
Autores principales: Masamsetti, V. Pragathi, Tam, Patrick P.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475837/
https://www.ncbi.nlm.nih.gov/pubmed/37671029
http://dx.doi.org/10.1016/j.crmeth.2023.100575
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author Masamsetti, V. Pragathi
Tam, Patrick P.L.
author_facet Masamsetti, V. Pragathi
Tam, Patrick P.L.
author_sort Masamsetti, V. Pragathi
collection PubMed
description Iwatsuki and colleagues have generated self-renewing pluripotent stem cells from the pre-gastrulation epiblast of the rat embryo and from other cellular sources: rat embryonic stem cells (rESCs) and epiblast-like cells derived from the rESCs. These rat epiblast-derived stem cells (rEpiSCs) display germ-line competence that is characteristic of mouse formative stem cells and early signature of specification of germ layer lineages typical of primed state mouse epiblast stem cells.
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spelling pubmed-104758372023-09-05 Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast Masamsetti, V. Pragathi Tam, Patrick P.L. Cell Rep Methods Preview Iwatsuki and colleagues have generated self-renewing pluripotent stem cells from the pre-gastrulation epiblast of the rat embryo and from other cellular sources: rat embryonic stem cells (rESCs) and epiblast-like cells derived from the rESCs. These rat epiblast-derived stem cells (rEpiSCs) display germ-line competence that is characteristic of mouse formative stem cells and early signature of specification of germ layer lineages typical of primed state mouse epiblast stem cells. Elsevier 2023-08-28 /pmc/articles/PMC10475837/ /pubmed/37671029 http://dx.doi.org/10.1016/j.crmeth.2023.100575 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Masamsetti, V. Pragathi
Tam, Patrick P.L.
Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
title Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
title_full Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
title_fullStr Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
title_full_unstemmed Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
title_short Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
title_sort rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475837/
https://www.ncbi.nlm.nih.gov/pubmed/37671029
http://dx.doi.org/10.1016/j.crmeth.2023.100575
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