A massively parallel approach for assessing CRISPR off-targets in vitro

In a recent issue of Med, Tian et al.(1) present AID-seq, an approach that enables massively parallel identification of off-targets for different CRISPR nucleases in vitro. By using a pooled strategy to simultaneously identify the on-/off-targets of multiple gRNAs, the authors could screen the most...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Shisheng, Huang, Xingxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475838/
https://www.ncbi.nlm.nih.gov/pubmed/37671012
http://dx.doi.org/10.1016/j.crmeth.2023.100561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475838/
https://www.ncbi.nlm.nih.gov/pubmed/37671012
http://dx.doi.org/10.1016/j.crmeth.2023.100561

Ejemplares similares