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Mapping antibody footprints using binding profiles

The increasing use of monoclonal antibodies (mAbs) in biology and medicine necessitates efficient methods for characterizing their binding epitopes. Here, we developed a high-throughput antibody footprinting method based on binding profiles. We used an antigen microarray to profile 23 human anti-inf...

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Detalles Bibliográficos
Autores principales: Azulay, Asaf, Cohen-Lavi, Liel, Friedman, Lilach M., McGargill, Maureen A., Hertz, Tomer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475849/
https://www.ncbi.nlm.nih.gov/pubmed/37671022
http://dx.doi.org/10.1016/j.crmeth.2023.100566

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