Synaptic expression of TAR-DNA-binding protein 43 in the mouse spinal cord determined using super-resolution microscopy

Amyotrophic Lateral Sclerosis (ALS) is characterised by a loss of motor neurons in the brain and spinal cord that is preceded by early-stage changes in synapses that may be associated with TAR-DNA-Binding Protein 43 (TDP-43) pathology. Cellular inclusions of hyperphosphorylated TDP-43 (pTDP-43) are...

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Detalles Bibliográficos
Autores principales: Broadhead, Matthew J., Ayvazian-Hancock, Ani, Doucet, Katherine, Kantelberg, Owen, Motherwell, Lesley, Zhu, Fei, Grant, Seth G. N., Horrocks, Mathew H., Miles, Gareth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475998/
https://www.ncbi.nlm.nih.gov/pubmed/37671010
http://dx.doi.org/10.3389/fnmol.2023.1027898

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