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TECPR1 is activated by damage‐induced sphingomyelin exposure to mediate noncanonical autophagy

Cells use noncanonical autophagy, also called conjugation of ATG8 to single membranes (CASM), to label damaged intracellular compartments with ubiquitin‐like ATG8 family proteins in order to signal danger caused by pathogens or toxic compounds. CASM relies on E3 complexes to sense membrane damage, b...

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Detalles Bibliográficos
Autores principales: Kaur, Namrita, de la Ballina, Laura Rodriguez, Haukaas, Håvard Styrkestad, Torgersen, Maria Lyngaas, Radulovic, Maja, Munson, Michael J, Sabirsh, Alan, Stenmark, Harald, Simonsen, Anne, Carlsson, Sven R, Lystad, Alf Håkon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476171/
https://www.ncbi.nlm.nih.gov/pubmed/37409525
http://dx.doi.org/10.15252/embj.2022113105

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