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TECPR1 is activated by damage‐induced sphingomyelin exposure to mediate noncanonical autophagy
Cells use noncanonical autophagy, also called conjugation of ATG8 to single membranes (CASM), to label damaged intracellular compartments with ubiquitin‐like ATG8 family proteins in order to signal danger caused by pathogens or toxic compounds. CASM relies on E3 complexes to sense membrane damage, b...
Autores principales: | Kaur, Namrita, de la Ballina, Laura Rodriguez, Haukaas, Håvard Styrkestad, Torgersen, Maria Lyngaas, Radulovic, Maja, Munson, Michael J, Sabirsh, Alan, Stenmark, Harald, Simonsen, Anne, Carlsson, Sven R, Lystad, Alf Håkon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476171/ https://www.ncbi.nlm.nih.gov/pubmed/37409525 http://dx.doi.org/10.15252/embj.2022113105 |
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