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HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunction

BACKGROUND: This study aimed to investigate the role of histone deacetylase 5 (HDAC5) in ventricular remodeling and explore the therapeutic potential of the HDAC5 inhibitor LMK235. METHODS: A transverse aortic constriction (TAC) mouse model and angiotensin II (Ang II)-treated H9C2 cells were used to...

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Detalles Bibliográficos
Autores principales:	Zhu, Chenxi, Piao, Zhehao, Jin, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476361/ https://www.ncbi.nlm.nih.gov/pubmed/37667300 http://dx.doi.org/10.1186/s13023-023-02896-y

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