Cargando…

Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy

BACKGROUND: Traumatic brain injury causes morbidity, mortality, and at least 2,500,000 yearly emergency department visits in the USA. Computerized tomography of the head is the gold standard to detect traumatic intracranial hemorrhage. Some are not diagnosed at the first scan, and they are denoted “...

Descripción completa

Detalles Bibliográficos
Autores principales: Bergenfeldt, Henrik, Forberg, Jakob Lundager, Lehtinen, Riikka, Anefjäll, Ebba, Vedin, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476369/
https://www.ncbi.nlm.nih.gov/pubmed/37667208
http://dx.doi.org/10.1186/s12245-023-00530-z
_version_ 1785100915626213376
author Bergenfeldt, Henrik
Forberg, Jakob Lundager
Lehtinen, Riikka
Anefjäll, Ebba
Vedin, Tomas
author_facet Bergenfeldt, Henrik
Forberg, Jakob Lundager
Lehtinen, Riikka
Anefjäll, Ebba
Vedin, Tomas
author_sort Bergenfeldt, Henrik
collection PubMed
description BACKGROUND: Traumatic brain injury causes morbidity, mortality, and at least 2,500,000 yearly emergency department visits in the USA. Computerized tomography of the head is the gold standard to detect traumatic intracranial hemorrhage. Some are not diagnosed at the first scan, and they are denoted “delayed intracranial hemorrhages. ” To detect these delayed hemorrhages, current guidelines for head trauma recommend observation and/or rescanning for patients on anticoagulation therapy but not for patients on antiplatelet therapy. The aim of this study was to investigate the prevalence and need for interventions of delayed intracranial hemorrhage after head trauma. METHODS: The study was a retrospective review of medical records of adult patients with isolated head trauma presenting at Helsingborg General Hospital between January 1, 2020, and December 31, 2020. Univariate statistical analyses were performed. RESULTS: In total, 1627 patients were included and four (0.25%, 95% confidence interval 0.06–0.60%) patients had delayed intracranial hemorrhage. One of these patients was diagnosed within 24 h and three within 2–30 days. The patient was diagnosed within 24 h, and one of the patients diagnosed within 2–30 days was on antiplatelet therapy. None of these four patients was prescribed anticoagulation therapy, and no intensive care, no neurosurgical operations, or deaths were recorded. CONCLUSION: Traumatic delayed intracranial hemorrhage is rare and consequences mild and antiplatelet and anticoagulation therapy might confer similar risk. Because serious complications appear rare, observing, and/or rescanning all patients with either of these medications can be debated. Risk stratification of these patients might have the potential to identify the patients at risk while safely reducing observation times and rescanning.
format Online
Article
Text
id pubmed-10476369
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-104763692023-09-05 Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy Bergenfeldt, Henrik Forberg, Jakob Lundager Lehtinen, Riikka Anefjäll, Ebba Vedin, Tomas Int J Emerg Med Research BACKGROUND: Traumatic brain injury causes morbidity, mortality, and at least 2,500,000 yearly emergency department visits in the USA. Computerized tomography of the head is the gold standard to detect traumatic intracranial hemorrhage. Some are not diagnosed at the first scan, and they are denoted “delayed intracranial hemorrhages. ” To detect these delayed hemorrhages, current guidelines for head trauma recommend observation and/or rescanning for patients on anticoagulation therapy but not for patients on antiplatelet therapy. The aim of this study was to investigate the prevalence and need for interventions of delayed intracranial hemorrhage after head trauma. METHODS: The study was a retrospective review of medical records of adult patients with isolated head trauma presenting at Helsingborg General Hospital between January 1, 2020, and December 31, 2020. Univariate statistical analyses were performed. RESULTS: In total, 1627 patients were included and four (0.25%, 95% confidence interval 0.06–0.60%) patients had delayed intracranial hemorrhage. One of these patients was diagnosed within 24 h and three within 2–30 days. The patient was diagnosed within 24 h, and one of the patients diagnosed within 2–30 days was on antiplatelet therapy. None of these four patients was prescribed anticoagulation therapy, and no intensive care, no neurosurgical operations, or deaths were recorded. CONCLUSION: Traumatic delayed intracranial hemorrhage is rare and consequences mild and antiplatelet and anticoagulation therapy might confer similar risk. Because serious complications appear rare, observing, and/or rescanning all patients with either of these medications can be debated. Risk stratification of these patients might have the potential to identify the patients at risk while safely reducing observation times and rescanning. Springer Berlin Heidelberg 2023-09-04 /pmc/articles/PMC10476369/ /pubmed/37667208 http://dx.doi.org/10.1186/s12245-023-00530-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Bergenfeldt, Henrik
Forberg, Jakob Lundager
Lehtinen, Riikka
Anefjäll, Ebba
Vedin, Tomas
Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy
title Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy
title_full Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy
title_fullStr Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy
title_full_unstemmed Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy
title_short Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy
title_sort delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention—even in antiplatelet or anticoagulation therapy
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476369/
https://www.ncbi.nlm.nih.gov/pubmed/37667208
http://dx.doi.org/10.1186/s12245-023-00530-z
work_keys_str_mv AT bergenfeldthenrik delayedintracranialhemorrhageafterheadtraumaseemsrareandrarelyneedsinterventioneveninantiplateletoranticoagulationtherapy
AT forbergjakoblundager delayedintracranialhemorrhageafterheadtraumaseemsrareandrarelyneedsinterventioneveninantiplateletoranticoagulationtherapy
AT lehtinenriikka delayedintracranialhemorrhageafterheadtraumaseemsrareandrarelyneedsinterventioneveninantiplateletoranticoagulationtherapy
AT anefjallebba delayedintracranialhemorrhageafterheadtraumaseemsrareandrarelyneedsinterventioneveninantiplateletoranticoagulationtherapy
AT vedintomas delayedintracranialhemorrhageafterheadtraumaseemsrareandrarelyneedsinterventioneveninantiplateletoranticoagulationtherapy