Loss of ACTL7A causes small head sperm by defective acrosome-acroplaxome-manchette complex

BACKGROUND: Actin-like 7 A (ACTL7A) is essential for acrosome formation, fertilization and early embryo development. ACTL7A variants cause acrosome detachment responsible for male infertility and early embryonic arrest. In this study, we aim to explore the additional functions of ACTL7A beyond the p...

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Detalles Bibliográficos
Autores principales: Zhang, Yini, Tang, Jianan, Wang, Xuemei, Sun, Yisi, Yang, Tianying, Shen, Xiaorong, Yang, Xinyue, Shi, Huijuan, Sun, Xiaoxi, Xin, Aijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476415/
https://www.ncbi.nlm.nih.gov/pubmed/37667331
http://dx.doi.org/10.1186/s12958-023-01130-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476415/
https://www.ncbi.nlm.nih.gov/pubmed/37667331
http://dx.doi.org/10.1186/s12958-023-01130-5

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