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Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study

BACKGROUND: Pulmonary Embolism (PE) is an acute and potentially fatal condition defined as the blockage of pulmonary arteries by an embolism that can be from various origins. OBJECTIVE: The present study aimed to investigate the findings of computed tomography pulmonary angiography (CTPA) and echoca...

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Autores principales: Sametzadeh, Mozhgan, Dadgostar, Sahar, Hanafi, Mohammad Ghasem, Mohammadi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476463/
https://www.ncbi.nlm.nih.gov/pubmed/37670847
http://dx.doi.org/10.1002/hsr2.1546
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author Sametzadeh, Mozhgan
Dadgostar, Sahar
Hanafi, Mohammad Ghasem
Mohammadi, Mohammad
author_facet Sametzadeh, Mozhgan
Dadgostar, Sahar
Hanafi, Mohammad Ghasem
Mohammadi, Mohammad
author_sort Sametzadeh, Mozhgan
collection PubMed
description BACKGROUND: Pulmonary Embolism (PE) is an acute and potentially fatal condition defined as the blockage of pulmonary arteries by an embolism that can be from various origins. OBJECTIVE: The present study aimed to investigate the findings of computed tomography pulmonary angiography (CTPA) and echocardiography in patients with acute PE. METHODS: The present cross‐sectional study included some patients with clinical manifestations of PE who underwent CTPA and echocardiography. The radiologic findings, PE severity, and outcome of the patients were recorded. Moreover, echocardiography was performed by an expert cardiologist using a high‐resolution device, while CTPA was performed by an expert radiologist using a 16‐slice device and a two‐step selective test bolus method. RESULTS: According to our findings, a total number of 147 patients were diagnosed with PE, including 44 (29.93%), 44 (29.93%), and 59 (40.14%) cases of mild, moderate, and severe PE, respectively. Moreover, 25 patients (17%) finally expired due to PE. Regarding the CTPA findings, 31 patients (21.1%) had septum flattening, while 35 (23.8%) had a septum deviation toward the left ventricle. Also, there were significant correlations between mortality and some CTPA findings, including severe PE (p < 0.001), the presence of septal deviation (p = 0.007), and higher diameters of the main pulmonary artery (p < 0.001) and right ventricle (p = 0.008). CONCLUSION: CTPA is a valid and accessible modality for diagnosing and evaluating PE in suspected patients. Moreover, several findings in CTPA could predict adverse outcomes, such as death, in patients with PE.
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spelling pubmed-104764632023-09-05 Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study Sametzadeh, Mozhgan Dadgostar, Sahar Hanafi, Mohammad Ghasem Mohammadi, Mohammad Health Sci Rep Original Research BACKGROUND: Pulmonary Embolism (PE) is an acute and potentially fatal condition defined as the blockage of pulmonary arteries by an embolism that can be from various origins. OBJECTIVE: The present study aimed to investigate the findings of computed tomography pulmonary angiography (CTPA) and echocardiography in patients with acute PE. METHODS: The present cross‐sectional study included some patients with clinical manifestations of PE who underwent CTPA and echocardiography. The radiologic findings, PE severity, and outcome of the patients were recorded. Moreover, echocardiography was performed by an expert cardiologist using a high‐resolution device, while CTPA was performed by an expert radiologist using a 16‐slice device and a two‐step selective test bolus method. RESULTS: According to our findings, a total number of 147 patients were diagnosed with PE, including 44 (29.93%), 44 (29.93%), and 59 (40.14%) cases of mild, moderate, and severe PE, respectively. Moreover, 25 patients (17%) finally expired due to PE. Regarding the CTPA findings, 31 patients (21.1%) had septum flattening, while 35 (23.8%) had a septum deviation toward the left ventricle. Also, there were significant correlations between mortality and some CTPA findings, including severe PE (p < 0.001), the presence of septal deviation (p = 0.007), and higher diameters of the main pulmonary artery (p < 0.001) and right ventricle (p = 0.008). CONCLUSION: CTPA is a valid and accessible modality for diagnosing and evaluating PE in suspected patients. Moreover, several findings in CTPA could predict adverse outcomes, such as death, in patients with PE. John Wiley and Sons Inc. 2023-09-04 /pmc/articles/PMC10476463/ /pubmed/37670847 http://dx.doi.org/10.1002/hsr2.1546 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Sametzadeh, Mozhgan
Dadgostar, Sahar
Hanafi, Mohammad Ghasem
Mohammadi, Mohammad
Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study
title Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study
title_full Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study
title_fullStr Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study
title_full_unstemmed Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study
title_short Application of CT pulmonary angiography and echocardiography in acute pulmonary embolism: A cross‐sectional study
title_sort application of ct pulmonary angiography and echocardiography in acute pulmonary embolism: a cross‐sectional study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476463/
https://www.ncbi.nlm.nih.gov/pubmed/37670847
http://dx.doi.org/10.1002/hsr2.1546
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