Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/mir-140-3p/TLR4 axis

It has been shown that dexmedetomidine (Dex) could attenuate postoperative cognitive dysfunction (POCD) via targeting circular RNAs (circRNAs). Circ-Shank3 has been found to be involved in the neuroprotective effects of Dex against POCD. However, the role of circ-Shank3 in POCD remains largely unkno...

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Detalles Bibliográficos
Autores principales: He, Guangbao, He, Yibo, Ni, Hongwei, Wang, Kai, Zhu, Yijun, Bao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476535/
https://www.ncbi.nlm.nih.gov/pubmed/37491974
http://dx.doi.org/10.4081/ejh.2023.3766

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