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Energy Metabolism Dysregulation in Chronic Kidney Disease

KEY POINTS: There is significant enrichment in metabolic pathways in early stages in the subtotal nephrectomy model of CKD. Proximal tubular mitochondrial respiration is suppressed likely from mitochondrial dysfunction in substrate utilization and ATP synthesis. There is significant suppression of p...

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Detalles Bibliográficos
Autores principales: Li, Ying, Gu, Wanjun, Hepokoski, Mark, Pham, Hai, Tham, Rick, Kim, Young Chul, Simonson, Tatum S., Singh, Prabhleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476685/
https://www.ncbi.nlm.nih.gov/pubmed/37222594
http://dx.doi.org/10.34067/KID.0000000000000153